Rush Orthopaedic Oncology, Rush University Medical Center, Chicago, IL, USA.
Clin Orthop Relat Res. 2010 Sep;468(9):2507-13. doi: 10.1007/s11999-010-1260-5. Epub 2010 Feb 10.
Although intercalary allograft reconstructions are commonly performed using intramedullary devices, they cannot generate compression across host-allograft junctions. Therefore, they sometimes are associated with gap formation and suboptimal healing conditions.
QUESTIONS/PURPOSES: We describe a new technique and present preliminary results for intercalary allograft reconstructions for tumors using a compressible intramedullary nail.
We retrospectively reviewed 10 patients (19 host-allograft junctions) who underwent intercalary allograft reconstruction using the compression nailing technique. Two patients were excluded as they had additional vascularized fibular autografts, leaving 15 junctions in eight patients for analysis. Three of the intercalary reconstructions had supplemental plate fixation at one junction. All patients received host bone reamings and cancellous allograft and one had bone marrow aspirate and demineralized bone matrix in addition to the cancellous allograft. The minimum followup was 3 months (mean, 18 months; range, 3-39 months).
Thirteen of 15 junctions healed without additional surgery. Two diaphyseal-diaphyseal junctions did not unite after allograft arthrodeses. One patient underwent revision for nonunion 8 months after the initial procedure, with subsequent healing. The second patient had no evidence of union at 6 months, after which he was lost to followup. There were no allograft fractures or infections in any reconstruction. One patient died of metastatic renal cell carcinoma, and one patient had multicentric local soft tissue recurrences of a periosteal osteosarcoma requiring resection.
Our early observations indicate newer compressible intramedullary nails reliably address junctional gap formation, providing for a high rate of union while retaining the long-term benefits of intramedullary stabilization.
Level IV, case series. See Guidelines for Authors for a complete description of levels of evidence.
虽然节段性同种异体骨重建通常采用髓内装置进行,但它们无法在宿主-异体骨交界处产生压缩。因此,它们有时会导致间隙形成和愈合条件不理想。
问题/目的:我们描述了一种新的技术,并介绍了使用可压缩髓内钉进行肿瘤节段性同种异体骨重建的初步结果。
我们回顾性分析了 10 例(19 个宿主-异体骨交界处)采用压缩钉技术进行节段性同种异体骨重建的患者。由于另外 2 例患者还接受了带血管化腓骨自体移植,因此排除这 2 例,留下 8 例患者的 15 个交界处进行分析。3 例节段性重建中有 1 个交界处采用附加钢板固定。所有患者均接受宿主骨扩髓和松质异体骨移植,其中 1 例除松质异体骨外还接受骨髓抽吸和脱钙骨基质。最短随访时间为 3 个月(平均 18 个月;范围 3-39 个月)。
15 个交界处中有 13 个无需进一步手术而愈合。2 例骨干-骨干交界处在异体骨融合后未愈合。1 例患者在初次手术后 8 个月因骨不连行翻修,随后愈合。第 2 例患者在 6 个月时无愈合迹象,随后失访。重建中无异体骨骨折或感染。1 例患者死于转移性肾细胞癌,1 例患者因骨膜骨肉瘤多中心局部软组织复发而行切除术。
我们的早期观察结果表明,新型可压缩髓内钉可靠地解决了交界处间隙形成问题,在保持髓内稳定长期获益的同时,提高了愈合率。
IV 级,病例系列。有关证据等级的完整描述,请参见作者指南。