Clinic for Angiology, University Hospital of Zurich, Switzerland.
Catheter Cardiovasc Interv. 2010 May 1;75(6):823-7. doi: 10.1002/ccd.22407.
To investigate primary success rates and long term follow-up of endovascular treatment of AngioSeal-related limb ischemia.
Current knowledge on optimal therapy of ischemic complications following application of AngioSeal is limited.
A single-center prospectively maintained database was retrospectively interrogated and AngioSeal-related complications requiring endovascular treatment over an 8-year-time period was identified.
Fifteen patients fulfilling the inclusion criteria were identified, resulting in an approximated incidence of 0.26% of all devices implanted at our institution. In all cases, the complication was managed successfully in the absence of complications. Eleven patients were treated with balloon angioplasty (PTA) and four with stent implantation because of suboptimal PTA results. Twelve patients were available for noninvasive vascular follow-up examination for a median time of 40 months postinterventionally. Only two patients needed a second intervention consisting of balloon angioplasty due to symptomatic restenosis. At final follow-up all patients were asymptomatic with no relevant restenosis.
Endovascular treatment for AngioSeal-related limb ischemia with or without stent implantation results in an excellent immediate and long-term clinical and hemodynamic outcome.
研究血管塞相关肢体缺血的血管内治疗的主要成功率和长期随访结果。
目前对于应用血管塞后缺血并发症的最佳治疗方法的了解有限。
回顾性分析了单中心前瞻性维护的数据库，并确定了在 8 年时间内需要血管内治疗的与血管塞相关的并发症。
确定了符合纳入标准的 15 名患者，在我院植入的所有装置中，其发病率约为 0.26%。所有病例均成功进行了治疗，无并发症发生。11 名患者因 PTA 效果不理想而接受球囊血管成形术（PTA）治疗，4 名患者因 PTA 效果不理想而接受支架植入治疗。12 名患者可进行非侵入性血管随访检查，平均随访时间为介入后 40 个月。仅有 2 名患者因症状性再狭窄而需要第二次介入治疗，包括球囊血管成形术。最终随访时，所有患者均无症状，无明显再狭窄。
血管塞相关肢体缺血的血管内治疗（包括支架植入）可获得极好的即刻和长期临床及血流动力学效果。
