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经主动脉经导管主动脉瓣植入术:真正“无入路选择”患者的一种新方法。

Transaortic transcatheter aortic valve implantation: a novel approach for the truly "no-access option" patients.

机构信息

Department of Cardiology and Angiology, Heart Center Siegburg, Siegburg, Germany.

出版信息

Catheter Cardiovasc Interv. 2010 Jun 1;75(7):1129-36. doi: 10.1002/ccd.22378.

DOI:10.1002/ccd.22378
PMID:20146328
Abstract

OBJECTIVES

The aim of this study was to test the safety and efficacy of the retrograde, minimally invasive, "transaortic" approach of transcatheter aortic valve implantation (TAVI) using the Medtronic CoreValve prosthesis (Medtronic, Minneapolis) as an alternative minimally invasive surgical access route.

BACKGROUND

TAVI is today recognized as an established percutaneous technique for patients with severe aortic valve stenosis (AS). However, as the number of patients screened for TAVI increases, many are found with absolutely no option for peripheral artery access.

METHODS

A new method of TAVI access, described as "transaortic" was performed in two patients A CoreValve prosthesis was implanted via the "transaortic" route. The patients were a 93- and a 84-year-old woman, both with severe PAOD. After a ministernotomy the ascending aorta was directly punctured. At the end, the access site was surgically sutured with the prepositioned sutures. The patients were at all times "off-pump" (beating heart procedure) and without IABP.

RESULTS

TAVI was successful in both cases, leading to a fall in the transvalvular gradient and there were no cases of mortality, stroke or myocardial infarction. The patients were extubated directly after the procedure, mobilized after 4 days, and were discharged home after 7 and 9 days.

CONCLUSIONS

In the rare occasion, where due to anatomical reasons transfemoral TAVI is not feasible, a minimally invasive "transaortic" approach, as described, provides an alternative option. This is especially true when the transapical route is not suitable (annulus >25 mm or contraindication to lateral thoracotomy).

摘要

目的

本研究旨在测试经导管主动脉瓣植入术(TAVI)逆行微创“经主动脉”方法的安全性和有效性,该方法使用美敦力 CoreValve 假体(美敦力,明尼苏达州)作为替代微创手术入路。

背景

TAVI 如今被认为是治疗严重主动脉瓣狭窄(AS)患者的一种成熟的经皮技术。然而,随着接受 TAVI 筛选的患者数量增加,许多患者发现根本没有外周动脉入路的选择。

方法

描述了一种新的 TAVI 入路方法,称为“经主动脉”。两名患者采用“经主动脉”途径植入 CoreValve 假体。这两名患者分别是一名 93 岁和一名 84 岁的女性,均患有严重的 PAOD。经小胸骨切开术后,直接穿刺升主动脉。最后,经预置缝线缝合入路部位。所有患者均始终处于“不停跳”(心脏跳动手术)状态,且未使用 IABP。

结果

在两种情况下,TAVI 均获得成功,导致跨瓣梯度下降,且无死亡、中风或心肌梗死病例。患者在手术后直接拔管,4 天后可下床活动,分别在术后 7 天和 9 天出院回家。

结论

在由于解剖原因经股动脉 TAVI 不可行的罕见情况下,如本文所述的微创“经主动脉”入路可提供替代选择。当经心尖途径不合适(瓣环>25mm 或不适合侧开胸)时尤其如此。

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