Division of Respiratory, Critical Care, and Occupational Pulmonary Medicine, University of Utah Health Sciences Center/School of Medicine, Salt Lake City, Utah 84132, USA.
Respirology. 2010 Apr;15(3):576-9. doi: 10.1111/j.1440-1843.2010.01717.x. Epub 2010 Feb 7.
Massive pulmonary embolism with haemodynamic instability has a high mortality. Traditionally these patients are treated with i.v. thrombolytic therapy. When this therapeutic approach is contraindicated, surgical embolectomy and most recently, percutaneous mechanical interventions are alternative treatment options. This case report presents a 73-year-old female with a residual hemiparesis secondary to a meningioma resection 45 days previously, who presented with progressive shortness of breath, accompanied by oppressive chest pain, hypotension, tachycardia and severe hypoxaemia. CT pulmonary angiogram confirmed a massive pulmonary embolism extending into the lobar branches bilaterally. The patient was treated with percutaneous mechanical thrombectomy with excellent haemodynamic and clinical outcomes.
大面积伴血流动力学不稳定的肺栓塞病死率高。传统上,此类患者采用静脉溶栓治疗。如果该治疗方法禁忌,手术取栓术和最近的经皮机械介入是替代治疗方法。本病例报告了 1 例 73 岁女性,45 天前因脑膜瘤切除术遗留偏瘫,以进行性呼吸困难、压迫性胸痛、低血压、心动过速和严重低氧血症为表现。CT 肺动脉造影证实为双侧肺叶分支内的大面积肺栓塞。患者接受了经皮机械血栓切除术治疗,血流动力学和临床结局均良好。