Myshkin K I, Amirova N M
Vopr Onkol. 1991;37(2):219-24.
The results of 676 radical operations for thyroid cancer are discussed. The choice of procedure was determined by tumor histology which was assessed using trephine biopsy. Extracapsular hemithyroidectomy was the basic procedure (420 out of 676 cases) used for the treatment of well-differentiated thyroid cancer affecting one lobe only. No fatalities were registered. Bilateral surgery was associated with paralysis of n. laryngeus in 1.5% of cases and with the nerve injury in 5.1%. With unilateral surgery, the parameter was 2.8%. The unilateral procedure offered the advantage of sparing the intact lobe which assured a decrease in thyrotropin and lower rates of relapse, hypothyrosis, hypoparathyroidism and paresis of n. laryngeus. Five-, ten- and twenty-year cumulative survival rates were 91.8, 87.8 and 71.6% whereas corrected rates--94, 93.6 and 92.9%, respectively.
本文讨论了676例甲状腺癌根治手术的结果。手术方式的选择取决于肿瘤组织学，通过环钻活检进行评估。腺外半甲状腺切除术是基本术式（676例中有420例），用于治疗仅累及一叶的高分化甲状腺癌。无死亡病例记录。双侧手术中，喉返神经麻痹发生率为1.5%，神经损伤发生率为5.1%。单侧手术时，这两个参数分别为2.8%。单侧手术的优点是保留了完整的叶，可确保促甲状腺激素降低，以及复发率、甲状腺功能减退、甲状旁腺功能减退和喉返神经麻痹发生率降低。5年、10年和20年的累积生存率分别为91.8%、87.8%和71.6%，校正率分别为94%、93.6%和92.9%。
