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海兔螺(Ilyanassa):一种重新兴起的发育研究模式生物。

The snail Ilyanassa: a reemerging model for studies in development.

作者信息

Gharbiah Maey, Cooley James, Leise Esther M, Nakamoto Ayaki, Rabinowitz Jeremy S, Lambert J David, Nagy Lisa M

机构信息

Department of Molecular and Cellular Biology, University of Arizona, Tucson, AZ 85721, USA.

出版信息

Cold Spring Harb Protoc. 2009 Apr;2009(4):pdb.emo120. doi: 10.1101/pdb.emo120.

Abstract

Ilyanassa obsoleta is a marine gastropod that is a long-standing and very useful model for studies of embryonic development. It is especially important as a model for the spiralian development program, a distinctive mode of early development shared by a large group of animal phyla, but poorly understood. Ilyanassa adults are readily obtainable and easy to keep in the laboratory, and they produce large numbers of embryos throughout most of the year. The embryos are amenable to classic embryological manipulation techniques as well as a growing number of molecular approaches. In this article, we present an overview of aspects of its biology and use as a model organism.

摘要

光壳海兔是一种海洋腹足纲动物,长期以来一直是胚胎发育研究中非常有用的模型。作为螺旋动物发育程序的模型,它尤为重要,螺旋动物发育程序是一大群动物门所共有的独特早期发育模式,但人们对此了解甚少。光壳海兔成虫很容易获得,且易于在实验室饲养,它们一年中的大部分时间都会产出大量胚胎。这些胚胎适用于经典的胚胎学操作技术以及越来越多的分子方法。在本文中,我们概述了其生物学特性以及作为模式生物的用途。

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