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一只美洲驼(小羊驼)患波萨达斯球孢子菌性角膜葡萄膜炎。

Coccidioides posadasii keratouveitis in a llama (Lama glama).

作者信息

Coster Martin E, Ramos-Vara José A, Vemulapalli Ramesh, Stiles Jean, Krohne Sheryl G

机构信息

Department of Veterinary Clinical Sciences, Purdue University School of Veterinary Medicine, 625 Harrison Street, West Lafayette, IN 47907, USA.

出版信息

Vet Ophthalmol. 2010 Jan;13(1):53-7. doi: 10.1111/j.1463-5224.2009.00747.x.

Abstract

A 7-year-old male llama was examined for a 3-month history of weight loss, and unilateral keratouveitis. Clinical examination revealed nonulcerative corneal stromal abscessation, corneal vascularization, corneal edema, miosis, posterior synechia, cataract, and fibrin in the anterior chamber of the right eye. The left eye was normal. Histopathology of the right eye following enucleation revealed pyogranulomatous keratouveitis with intralesional fungal spherules consistent with Coccidioides spp. PCR amplification with DNA sequencing confirmed Coccidioides posadasii infection. To the authors' knowledge, this is the first reported case of ocular coccidioidomycosis in a llama.

摘要

对一头7岁雄性美洲驼进行检查,其有3个月体重减轻及单侧角膜葡萄膜炎病史。临床检查发现右眼有非溃疡性角膜基质脓肿、角膜血管化、角膜水肿、瞳孔缩小、虹膜后粘连、白内障及前房纤维蛋白。左眼正常。摘除右眼后的组织病理学检查显示为脓性肉芽肿性角膜葡萄膜炎,病变内有与球孢子菌属相符的真菌小球。DNA测序的聚合酶链反应(PCR)扩增证实为波萨达斯球孢子菌感染。据作者所知,这是美洲驼眼部球孢子菌病的首例报道病例。

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