Kecskés István
Fovárosi Onkormányzat Szent János Kórház és Eszak-budai Egyesített Kórházak, Pszichiátriai Osztály, Budapest, Hungary.
Neuropsychopharmacol Hung. 2009 Dec;11(4):259-63.
Antipsychotics have been used in the therapy of schizophrenia and bipolar disorder and several second generation antipsychotics (SGA) are already available in Hungary. The clinical trials' results are confusing in regarding the differences in the efficacy of the SGA's, but the differences in their side-effects are clear. Considering its most important side-effects, such as extrapyramidal symptoms, weight gain, metabolic syndrome and prolactin level elevation, quetiapine has a fairly good side effect profile, and can therefore be recommended especially in case of bipolar patients who are highly sensitive towards side effects.. In our case-report, we present four patients who were successfully treated with quetiapine for their psychotic mood elevation.
抗精神病药物已被用于治疗精神分裂症和双相情感障碍,匈牙利已有几种第二代抗精神病药物(SGA)可供使用。关于SGA疗效的差异,临床试验结果令人困惑,但它们副作用的差异是明显的。考虑到其最重要的副作用,如锥体外系症状、体重增加、代谢综合征和催乳素水平升高,喹硫平具有相当好的副作用特征,因此尤其可以推荐给对副作用高度敏感的双相情感障碍患者。在我们的病例报告中,我们介绍了四名因精神病性情绪高涨而成功接受喹硫平治疗的患者。