韩国人群脊柱手术后谵妄。
Delirium after spinal surgery in Korean population.
机构信息
Department of Orthopaedic Surgery, Hanyang University College of Medicine, Seoul, Korea.
出版信息
Spine (Phila Pa 1976). 2010 Aug 15;35(18):1729-32. doi: 10.1097/BRS.0b013e3181c423fc.
STUDY DESIGN
The incidence and risk factors of postoperative delirium were retrospectively examined in patients who had spine surgery for degenerative lumbar disease.
OBJECTIVE
The aim of this study is to examine the incidence, pre- and postoperative risk factors and clinical results of postoperative delirium after spine surgery.
SUMMARY OF BACKGROUND DATA
Postoperative delirium is of great concern in older patients. Patients with postoperative delirium tend to have delay in functional restoration and difficulty in postoperative care. But to author's knowledge this is the first report to postoperative delirium after spine surgery in South Korean population.
METHODS
Eighty-one patients over 70 years of age, who underwent spinal fusion for degenerative lumbar disease from November 2000 and March 2007 were selected. We analyzed the relation between postoperative delirium and such variables as operation time, intraoperative blood loss and transfusion, fusion level, comorbidity and laboratory data checked before surgery and at 1 day after surgery.
RESULTS
Postoperative delirium was found in 11 patients (13.6%). There were significant relationships between postoperative delirium and comorbidity such as cerebral vascular disease and gastric ulcer. Hemoglobin and hematocrit levels at 1 day after surgery and albumin level before surgery was significantly lower than in control group. Oswestry disability index was improved from 50.4% to 27.6% in delirium group and from 48.5% to 24.9% in control group. Hospitalization period was significantly longer in delirium group.
CONCLUSION
History of cerebral vascular disease, low hemoglobin and hematocrit levels at 1 day after surgery, and bad nutritional status were risk factors for delirium. As it is of great concern in older patients, careful observation is necessary for the management of patients with risk factors for delirium.
研究设计
回顾性分析退行性腰椎疾病行脊柱手术患者术后谵妄的发生率及危险因素。
目的
本研究旨在探讨脊柱手术后谵妄的发生率、围手术期危险因素和临床结果。
背景资料总结
术后谵妄在老年患者中备受关注。术后谵妄患者往往功能恢复延迟,术后护理困难。但据作者所知,这是第一份关于韩国人群脊柱手术后谵妄的报告。
方法
选择 2000 年 11 月至 2007 年 3 月期间因退行性腰椎疾病行脊柱融合术的 81 例 70 岁以上患者。我们分析了术后谵妄与手术时间、术中失血量和输血、融合节段、合并症以及术前和术后 1 天的实验室检查结果等变量之间的关系。
结果
11 例(13.6%)患者发生术后谵妄。术后谵妄与合并症(如脑血管疾病和胃溃疡)有显著关系。术后 1 天血红蛋白和红细胞压积水平及术前白蛋白水平显著低于对照组。谵妄组 Oswestry 功能障碍指数从 50.4%改善至 27.6%,对照组从 48.5%改善至 24.9%。谵妄组的住院时间明显延长。
结论
脑血管疾病史、术后 1 天血红蛋白和红细胞压积水平低、营养状况差是谵妄的危险因素。由于老年患者中这一问题备受关注,因此对有谵妄危险因素的患者进行仔细观察非常必要。