Center for Evolutionary Functional Genomics, The Biodesign Institute, and Department of Chemistry and Biochemistry at Arizona State University, Tempe, Arizona 85287-5301, USA.
Chem Biodivers. 2010 Feb;7(2):245-58. doi: 10.1002/cbdv.200900281.
This review examines acyclic nucleoside analogs as therapeutic agents, potential progenitor candidates to RNA, and novel building blocks for nucleic-acid nanotechnology. Together, these areas of research provide new insights into the structural and functional properties of nucleic acids and suggest new paradigms for nucleic acid self-assembly.
这篇综述考察了作为治疗剂的无环核苷类似物、潜在的 RNA 前体候选物以及核酸纳米技术的新型构建块。这些研究领域共同为核酸的结构和功能特性提供了新的见解，并为核酸自组装提出了新的范例。
