Alahuhta S, Räsänen J, Jouppila R, Jouppila P, Kangas-Saarela T, Hollmen A I
Department of Obstetrics and Gynaecology, University of Oulu, Finland.
Br J Anaesth. 1991 Mar;66(3):319-23. doi: 10.1093/bja/66.3.319.
We have studied the effects of extradural anaesthesia with bupivacaine (plain) in eight healthy parturients undergoing elective Caesarean section, on blood flow in maternal uterine and placental arcuate arteries and in fetal umbilical, renal and middle cerebral arteries, using a colour Doppler technique. Simultaneously, fetal myocardial function was investigated by M-mode echocardiography. Maternal and fetal blood velocity waveform indices did not change significantly. We found no changes in fetal myocardial function with extradural anaesthesia, except for an increase in the right ventricular inner end-diastolic dimensions. These results suggest that extradural anaesthesia has no detrimental effects on uteroplacental and fetal circulations in the uncomplicated pregnancy when maternal hypotension is avoided with rapid prehydration.
我们使用彩色多普勒技术,研究了布比卡因(普通型)硬膜外麻醉对八名择期剖宫产的健康产妇的子宫和胎盘弓状动脉血流以及胎儿脐动脉、肾动脉和大脑中动脉血流的影响。同时,通过M型超声心动图研究胎儿心肌功能。产妇和胎儿的血流速度波形指标没有显著变化。我们发现硬膜外麻醉对胎儿心肌功能没有影响,只是右心室内舒张末期内径有所增加。这些结果表明,在避免产妇低血压的情况下,通过快速预补液,硬膜外麻醉对正常妊娠的子宫胎盘和胎儿循环没有不利影响。