3rd Department of Surgery, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
BMC Gastroenterol. 2010 Feb 14;10:18. doi: 10.1186/1471-230X-10-18.
Individuals with impaired immunity are at higher risk of perianal diseases. Concerning complex anal fistulas impaired healing and complication rates are also higher. Definitive treatment of a fistula aims controlling the purulent discharge and prevents its recurrence. It depends mainly on the trajectory of the fistula and the underlying disease. We present a case of a HIV-positive patient with a complex extrasphincteric anal fistula who was treated successfully with fibrin glue application. We further, discuss tips and tricks when applying fibrin glue as plugging material in complex anal fistulas.
A sixty-one-year-old HIV-positive male referred to us for warts and extrasphincteric fistula. Because of the patients' immunological status, we opted against surgery and recommended fibrin glue plugging. The patient was discharged the same day. A follow-up examination was performed 5 days after the initial fibrin glue application showing that the fistula canal was obstructed. Three months and a year post-intervention the fistula tract remains closed.
The best treatment for a disease gives at least the same result with the other treatments with minimised risk for the life of the patient and minimal application effort. Conservative closure of fistula with fibrin plugging is simple, safe and with less morbidity than surgery. Our patient was successfully treated without endangering his life despite his precarious medical state. Not everybody believes in the effectiveness of fibrin glue application, however we consider this solution in cases of complex fistulas at least as primary procedure in special populations such as the immunosupressed.
免疫功能受损的个体患肛周疾病的风险更高。对于复杂的肛痿,愈合不良和并发症的发生率也更高。瘘管的确定性治疗旨在控制脓性分泌物的排出,并防止其复发。它主要取决于瘘管的轨迹和潜在的疾病。我们报告了一例 HIV 阳性患者患有复杂的肛旁痿,该患者成功地接受了纤维蛋白胶应用治疗。我们进一步讨论了在复杂肛痿中应用纤维蛋白胶作为填塞材料时的技巧和窍门。
一名 61 岁的 HIV 阳性男性因疣和肛旁痿而被转介给我们。由于患者的免疫状态,我们选择不进行手术,并建议使用纤维蛋白胶填塞。患者当天出院。初次纤维蛋白胶应用后 5 天进行了随访检查,显示瘘管腔被阻塞。干预后 3 个月和 1 年,痿管通道仍然关闭。
对于一种疾病的最佳治疗方法至少与其他治疗方法具有相同的效果,同时最大限度地降低对患者生命的风险和最小的应用努力。用纤维蛋白塞闭合痿管简单、安全,且发病率低于手术。尽管我们的患者的医疗状况不稳定,但他没有危及生命,成功地接受了治疗。并非每个人都相信纤维蛋白胶应用的有效性,但我们认为在特殊人群(如免疫抑制人群)中,对于复杂痿管,这种解决方案至少可以作为首选方法。