Department of Orthodontics, University of Wuerzburg, Wuerzburg, Germany.
Am J Orthod Dentofacial Orthop. 2010 Feb;137(2):168.e1-8; discussion 168-9. doi: 10.1016/j.ajodo.2008.11.023.
The aim of this controlled study was to analyze the degree and localization of 3-dimensional (3D) facial asymmetry in adult patients with cleft lip and palate (CLP) compared with a control group and its impact on the visual perception of faces.
The degree of 3D asymmetry was analyzed with a novel method without landmarks in 18 adults with complete unilateral CLP and 18 adults without congenital anomalies. Furthermore, the CLP and control faces were rated for appearance, symmetry, and facial expression by 30 participants.
The results showed that adults with CLP had significantly greater asymmetry in their facial soft tissues compared with the control group. Moreover, the lower face, and particularly the midface, had greater asymmetry in the CLP patients. The perceptual ratings showed that adults with CLP were judged much more negatively than those in the control group.
With sophisticated 3D analysis, the real morphology of a face can be calculated and asymmetric regions precisely identified. The greatest asymmetry in CLP patients is in the midface. These results underline the importance of symmetry in the perception of faces. In general, the greater the facial asymmetry near the midline of the face, the more negative the evaluation of the face in direct face-to-face interactions.
本对照研究旨在分析成年唇腭裂（CLP）患者与对照组相比三维（3D）面部不对称的程度和定位，并分析其对面部视觉感知的影响。
本研究使用一种新颖的无标志方法分析了 18 名完全单侧 CLP 成年患者和 18 名无先天畸形的成年患者的 3D 不对称程度。此外，30 名参与者对 CLP 面部和对照组的外观、对称性和面部表情进行了评分。
结果表明，CLP 患者的面部软组织不对称程度明显大于对照组。此外，CLP 患者的下部脸，特别是中部脸，不对称程度更大。感知评分显示，CLP 患者的判断比对照组更负面。
通过复杂的 3D 分析，可以计算出面部的真实形态，并精确识别不对称区域。CLP 患者最大的不对称性在中面部。这些结果强调了对称性对面部感知的重要性。一般来说，面部中线附近的面部不对称程度越大，在面对面的直接互动中对面部的评价就越负面。
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