National Key Laboratory of Crop Genetic Improvement and National Centre of Plant Gene Research (Wuhan), Huazhong Agricultural University, Wuhan, China.
Curr Opin Plant Biol. 2010 Apr;13(2):186-92. doi: 10.1016/j.pbi.2010.01.002. Epub 2010 Feb 10.
Hybrid sterility is the most common form of postzygotic reproductive isolation in plants. The best-known example is perhaps the hybrid sterility between indica and japonica subspecies of Asian cultivated rice (Oryza sativa L.). Major progress has been reported recently in rice in identifying and cloning hybrid sterility genes at two loci regulating female and male fertility, respectively. Genetic analyses and molecular characterization of these genes, together with the results from other model organisms especially Drosophila, have advanced the understanding of the processes underlying reproductive isolation and speciation. These findings also have significant implications for crop genetic improvement, by providing the feasibility and strategies for overcoming intersubspecific hybrid sterility thus allowing the development of intersubspecific hybrids.
杂种不育是植物中最常见的合子后生殖隔离形式。最著名的例子可能是亚洲栽培稻（Oryza sativa L.）的籼稻和粳稻亚种之间的杂种不育。最近在水稻中，在分别调节雌性和雄性育性的两个基因座上鉴定和克隆杂种不育基因方面取得了重大进展。这些基因的遗传分析和分子特征，以及来自其他模式生物（尤其是果蝇）的结果，促进了对生殖隔离和物种形成过程的理解。这些发现对于作物遗传改良也具有重要意义，因为它提供了克服亚种间杂种不育的可行性和策略，从而允许开发亚种间杂种。
