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与 HIV 诊断后延迟进入初级 HIV 医疗保健相关的因素。

Factors associated with delayed entry into primary HIV medical care after HIV diagnosis.

机构信息

Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.

出版信息

AIDS. 2010 Mar 27;24(6):928-30. doi: 10.1097/QAD.0b013e328337b116.

Abstract

The aim of the study was to assess the median time between HIV diagnosis and entry into primary HIV medical care in a large urban area and to assess the potential individual, diagnosing facility, and community level factors influencing entry into care. One thousand two hundred and sixty-six individuals diagnosed with HIV in Philadelphia between 1 July 2005 and 30 June 2006 were followed until entry into care through 15 June 2007. Time to entry into care was calculated as a survival time variable and was defined as the time in months between the date of HIV diagnosis and the date more than 3 weeks after diagnosis when a CD4 cell count or percentage and/or HIV viral load were obtained. The median time to entry into care for all individuals was 8 months, with a range of 1-26 months. Factors associated with delayed entry into care included age more than 40 years [hazard ratio (HR) = 0.85; 95% confidence interval (CI) = 0.75-0.97] and diagnosis as an inpatient in the hospital (HR = 0.37; 95% CI = 0.37-0.57). Factors associated with earlier entry into care included Hispanic ethnicity (HR = 1.39; 95% CI = 1.05-1.84), male sex with men as HIV transmission risk factor (HR = 1.27; 95% CI = 1.03-1.56), and residence in a census tract with a high poverty rate (HR = 1.68; 95% CI = 1.22-2.30). Individuals newly diagnosed with HIV in Philadelphia demonstrated marked delays in accessing care highlighting the tremendous need for interventions to improve overall linkage. These interventions should especially be targeted at those aged more than 40 years and those diagnosed in the hospital.

摘要

本研究旨在评估在一个大型城市地区,艾滋病毒诊断和进入初级艾滋病毒医疗保健之间的中位数时间,并评估影响进入医疗保健的潜在个体、诊断机构和社区层面的因素。2005 年 7 月 1 日至 2006 年 6 月 30 日期间,在费城被诊断出艾滋病毒的 1266 人被跟踪,直至 2007 年 6 月 15 日进入医疗保健。进入医疗保健的时间被计算为生存时间变量,定义为从艾滋病毒诊断日期到诊断后超过 3 周获得 CD4 细胞计数或百分比和/或艾滋病毒病毒载量的日期之间的月份数。所有个体进入医疗保健的中位数时间为 8 个月,范围为 1-26 个月。与延迟进入医疗保健相关的因素包括年龄超过 40 岁[风险比(HR)= 0.85;95%置信区间(CI)= 0.75-0.97]和在医院住院诊断(HR = 0.37;95%CI = 0.37-0.57)。与较早进入医疗保健相关的因素包括西班牙裔(HR = 1.39;95%CI = 1.05-1.84)、男性、男男性行为作为艾滋病毒传播风险因素(HR = 1.27;95%CI = 1.03-1.56)和居住在贫困率高的普查区(HR = 1.68;95%CI = 1.22-2.30)。在费城新诊断出艾滋病毒的个体在获得医疗保健方面表现出明显的延迟,突出表明需要采取干预措施来改善整体联系。这些干预措施应特别针对年龄超过 40 岁和在医院诊断出的个体。

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