Scott H J, Coleridge Smith P D, Scurr J H
Department of Surgery, University College and Middlesex School of Medicine, Middlesex Hospital, London, UK.
Br J Surg. 1991 Feb;78(2):210-1. doi: 10.1002/bjs.1800780226.
The number of white blood cells per mm2 has been determined in serial histological slides taken from punch biopsies of skin from the goiter region in patients with varicose veins. In eight patients the varicose veins were complicated by lipodermatosclerosis of the skin, and in a further six there was a history of ulceration. In uncomplicated varicose veins there was a median of 6 white blood cells per mm2, in patients with lipodermatosclerosis there were 45 white blood cells per mm2, and where there was a history of ulceration, 217 white blood cells per mm2. No change in white blood cell content was observed after the venous pressure was raised for 30 min by sitting the patient with the lower limb dependent. White blood cell infiltration of the skin is associated with lipodermatosclerotic changes caused by venous insufficiency.
对患有静脉曲张的患者甲状腺肿区域皮肤穿刺活检所取的系列组织学切片，测定了每平方毫米白细胞的数量。8例患者的静脉曲张并发了皮肤脂肪硬化症，另有6例有溃疡病史。在无并发症的静脉曲张患者中，每平方毫米白细胞中位数为6个，脂肪硬化症患者为每平方毫米45个白细胞，有溃疡病史的患者为每平方毫米217个白细胞。让患者下肢下垂坐立30分钟使静脉压升高后，未观察到白细胞含量的变化。皮肤白细胞浸润与静脉功能不全引起的脂肪硬化性改变相关。
