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CLOVES 综合征的围产期临床和影像学特征。

Perinatal clinical and imaging features of CLOVES syndrome.

机构信息

Department of Pediatric Surgery, Virgen del Rocio Children's Hospital, Seville, Spain.

出版信息

Pediatr Radiol. 2010 Aug;40(8):1436-9. doi: 10.1007/s00247-010-1559-0. Epub 2010 Feb 13.

DOI:10.1007/s00247-010-1559-0
PMID:20155260
Abstract

We report a neonate with antenatal imaging features suggestive of CLOVES syndrome. Postnatal clinical and imaging findings confirmed the diagnosis, with the constellation of truncal overgrowth, cutaneous capillary malformation, lymphatic and musculoskeletal anomalies. The clinical, radiological and histopathological findings noted in this particular phenotype help differentiate it from other overgrowth syndromes with complex vascular anomalies.

摘要

我们报告了一例具有产前影像学特征提示 CLOVES 综合征的新生儿。产后临床和影像学检查结果证实了这一诊断,存在躯干过度生长、皮肤毛细血管畸形、淋巴和肌肉骨骼异常。在这种特殊表型中观察到的临床、放射学和组织病理学发现有助于将其与其他具有复杂血管异常的过度生长综合征区分开来。

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A Review on Cutaneous and Musculoskeletal Manifestations of CLOVES Syndrome.CLOVES综合征的皮肤和肌肉骨骼表现综述
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本文引用的文献

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CLOVE(S) syndrome: expanding the acronym.
Am J Med Genet A. 2009 Feb;149A(2):294; author reply 295. doi: 10.1002/ajmg.a.32632.
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Characterization of a distinct syndrome that associates complex truncal overgrowth, vascular, and acral anomalies: a descriptive study of 18 cases of CLOVES syndrome.一种伴有复杂躯干过度生长、血管和肢体末端异常的独特综合征的特征:18例CLOVES综合征的描述性研究
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Newly delineated syndrome of congenital lipomatous overgrowth, vascular malformations, and epidermal nevi (CLOVE syndrome) in seven patients.7例患者中发现的先天性脂肪瘤过度生长、血管畸形和表皮痣(CLOVE综合征)新界定综合征。
面部浸润性脂肪瘤病的多个组织中存在体细胞 PIK3CA 突变。
Pediatr Res. 2017 Nov;82(5):850-854. doi: 10.1038/pr.2017.155. Epub 2017 Aug 2.
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CLOVES Syndrome: Severe Neonatal Presentation.克洛夫斯综合征:严重的新生儿表现。
J Clin Diagn Res. 2017 Apr;11(4):TR01-TR03. doi: 10.7860/JCDR/2017/23801.9719. Epub 2017 Apr 1.
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A rare newly described overgrowth syndrome with vascular malformations-Cloves syndrome.一种罕见的、新描述的伴有血管畸形的过度生长综合征——CLOVES综合征。
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