J Neurol. 2010 Jun;257(6):1045-6. doi: 10.1007/s00415-010-5487-6. Epub 2010 Feb 13.
We report the case of a 77-year-old immuno-competent man who developed herpes zoster in the maxillary and mandibular branches of the trigeminal nerve. Within 3 weeks, he developed ipsilateral peripheral facial palsy, hearing loss, vesicles over the external auditory canal, and pain in the face and ear. A T(2)-weighted MRI of the brain revealed a hyper-intense lesion at the right medulla corresponding to the spinal trigeminal nucleus and tract. Gadolinium enhancement was seen over the right facial nerve. These lesions suggest a possibility of transaxonal spread of the varicella zoster virus between the trigeminal nerve, the facial nerve, and the spinal trigeminal nucleus and tract.
我们报告了一例 77 岁免疫功能正常的男性患者,他在三叉神经的上颌支和下颌支发生带状疱疹。3 周内,他出现同侧周围性面瘫、听力损失、外耳道水疱和面部及耳部疼痛。大脑 T2 加权 MRI 显示右延髓内与脊髓三叉神经核和束相对应的高信号病变。右侧面神经可见钆增强。这些病变提示水痘带状疱疹病毒在三叉神经、面神经和脊髓三叉神经核和束之间可能发生轴突间传播。