中年人一生的物质滥用和 5 年内出现突发健康问题的发生率。
Lifetime substance misuse and 5-year incidence rates of emergent health problems among middle-aged adults.
机构信息
Carver College of Medicine, Department of Psychiatry, University of Iowa, Iowa City, IA 52242, USA.
出版信息
J Addict Dis. 2009 Oct;28(4):320-31. doi: 10.1080/10550880903182796.
Understanding the impact of prior substance misuse on emergent health problems is important to the implementation of effective preventive care. This study examined the 5-year incidence rates using a sample of middle-aged adult adoptees (N = 309, mean(age) = 44.32, standard deviation(age) = 7.28). Subjects reported on health problems at two waves of study. DSM-IV diagnoses of substance misuse were obtained using a semi-structured diagnostic interview. Finally, health services utilization and perceived health status were collected. Lifetime diagnoses of marijuana and other non-marijuana substance misuse significantly predicted new occurrences of cardiovascular and metabolic disease. Alcohol misuse predicted earlier onset of cardiovascular disease among men. Marijuana and other non-marijuana drugs predicted earlier onset of cardiovascular disease for men and women. Finally, marijuana and other non-marijuana drugs predicted earlier onset of metabolic disease among men. Substance misuse did not predict health services utilization despite higher rates of disease. These findings emphasize the need to assess lifetime substance misuse when evaluating health risks associated with use.
了解先前物质滥用对紧急健康问题的影响对于实施有效的预防保健措施非常重要。本研究使用中年成年被收养者样本（N=309，平均年龄（age）=44.32，年龄标准差（age）=7.28），考察了 5 年的发病率。受试者在研究的两个阶段报告了健康问题。使用半结构化诊断访谈获得了物质滥用的 DSM-IV 诊断。最后，收集了卫生服务的利用情况和健康状况感知。终生诊断的大麻和其他非大麻物质滥用显著预测了心血管和代谢疾病的新发病例。酒精滥用预测了男性心血管疾病的发病更早。大麻和其他非大麻药物预测了男性和女性心血管疾病的发病更早。最后，大麻和其他非大麻药物预测了男性代谢性疾病的发病更早。尽管疾病发病率较高，但物质滥用并未预测卫生服务的利用。这些发现强调了在评估与使用相关的健康风险时，需要评估终生物质滥用。
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