Vaid Lakshmi, Gupta Manish, Gupta Neelima, Singh P P
Department of Otorhinolaryngology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India.
Ear Nose Throat J. 2010 Jan;89(1):E23-6.
Cervical lymphangioma in adults is a rare, benign tumor. Traditionally, the most accepted treatment has been surgical excision. However, when lymphangioma infiltrates vital neurovascular structures, excision is difficult and recurrence rates are high. The most common alternate treatment is intralesional injection of sclerosing agents, which has resulted in good outcomes in children. However, until now, no report of such treatment in adults has been published. We describe the case of a 60-year-old woman who presented with two lymphangiomas in the cervical area-one in the upper cervical area just below the angle of the mandible and the other in the submental area. She was treated with an intralesional injection of 1 mg/kg of bleomycin at both sites. Fifteen days later, the submental swelling had remitted completely and the other swelling had been reduced by 50%; 2 weeks later, a second injection was administered to the remaining swelling. At 6 months of follow-up, both lymphangiomas were in complete remission.
成人颈部淋巴管瘤是一种罕见的良性肿瘤。传统上，最被认可的治疗方法是手术切除。然而，当淋巴管瘤浸润重要的神经血管结构时，切除困难且复发率高。最常见的替代治疗方法是瘤内注射硬化剂，这在儿童中已取得良好效果。然而，迄今为止，尚未有关于成人此类治疗的报道。我们描述了一名60岁女性的病例，她颈部有两个淋巴管瘤，一个位于下颌角下方的上颈部区域，另一个位于颏下区域。两个部位均接受了1mg/kg博来霉素的瘤内注射治疗。15天后，颏下肿胀完全消退，另一个肿胀减轻了50%；2周后，对剩余肿胀部位进行了第二次注射。随访6个月时，两个淋巴管瘤均完全缓解。
