Division of Cardiac and Vascular Sciences, St George's University of London, Cranmer Terrace, London, UK.
Clin Cardiol. 2010 Mar;33(3):E19-24. doi: 10.1002/clc.20421.
The multielectrode array (MEA) enables noncontact mapping of cardiac arrhythmias; our experience is reviewed and reported.
The MEA has a role as first line therapy in multiple arrhythmias.
Retrospective and prospective analysis of all consecutive cases performed using the MEA over a 6 year period.
Electrophysiological study and catheter ablation, 46% under general anaesthesia, using radiofrequency (RF), cryothermal and low energy direct current (DC) was performed in 66 procedures on 31 females and 29 males, average age 50.2 yrs (19.3-81.6); 8 patients underwent multiple procedures. 24 patients (36%) had undergone past ablation for the same arrhythmia. A wide variety of arrhythmias from all chambers were treated, majority right atrial (56%) and right ventricular (29%). Procedural success was complete in 77.4% and partial/indeterminate in 11.3%, highest in right atrial tachycardia, right ventricular outflow tract ectopy and typical atrial flutter (79, 82 and 100%). RF energy was most commonly used (67%) and DC carried 100% success. Ablation was delivered at 'early activation' and 'breakout' in focal arrhythmias. In re-entrant circuits linear ablation transecting path of activation extending to regions of functional/anatomic block was performed. Two of 7 complications were attributed to the MEA: groin haematomas. At mean 12.4 mo follow up 56% were arrhythmia free, 15% asymptomatic or minimally symptomatic and 12 patients had new arrhythmias.
The MEA is effective, safe and suitable for first line therapy in multiple cardiac arrhythmias particularly in the right heart. Further study is warranted comparing it to other mapping techniques.
多电极阵列(MEA)可实现心律失常的非接触式映射;我们回顾并报告了相关经验。
MEA 在多种心律失常中可作为一线治疗方法。
对过去 6 年间使用 MEA 进行的所有连续病例进行回顾性和前瞻性分析。
在 66 次手术中对 31 名女性和 29 名男性进行了电生理研究和导管消融,其中 46%在全身麻醉下进行,使用射频(RF)、冷冻和低能量直流电(DC),患者平均年龄 50.2 岁(19.3-81.6);8 名患者接受了多次手术。24 名患者(36%)曾因同一心律失常接受过消融治疗。治疗的心律失常种类繁多,来自所有腔室,其中大多数为右心房(56%)和右心室(29%)。77.4%的手术取得了完全成功,11.3%的手术取得了部分/不确定的成功,右房性心动过速、右室流出道异位和典型房扑的成功率最高(79%、82%和 100%)。最常使用的是 RF 能量(67%),而 DC 则实现了 100%的成功。在局灶性心律失常中,消融是在“早期激活”和“突破”处进行的。在折返性环路上,进行了线性消融,横切激活路径,延伸至功能/解剖阻滞区域。7 例并发症中有 2 例与 MEA 有关:腹股沟血肿。平均 12.4 个月的随访中,56%的患者无心律失常,15%的患者无症状或症状轻微,12 名患者出现新的心律失常。
MEA 有效、安全,适用于多种心律失常的一线治疗,特别是在右心。有必要进一步研究将其与其他映射技术进行比较。