Johnson Brandy J, Lin Baochuan, Bongard Jason E
Center for Bio/Molecular Science and Engineering, Code 6900, Naval Research Laboratory, Washington, DC 20375, USA.
Recent Pat Biotechnol. 2010 Jun;4(2):112-24. doi: 10.2174/187220810791110732.
Vaccinium is a genus of shrubs several of which, including cranberry, lingonberry, and blueberry, produce edible fruit. Consumption of the fruit of these plants and juices pressed from it has long been known to have healthful effects. A number of functional compounds have been extracted from the fruits and seeds of these plants. Anthocyanidins and related compounds have been reported to possess antimicrobial, antioxidant, and anti-inflammatory properties. Extracts of the fruits have been applied to the inhibition of non-enzymatic glycosylation in anti-aging preparations. The oil of the cranberry seed is high in antioxidants and is a source of omega-3, -6, and -9 fatty acids making it an attractive cosmetics component. The inhibition of tumor growth, angiogenesis, and metastasis by extracts of these fruits has been described. Extracts of the plants have also been applied to the development of antimicrobial paints and coatings. Here, we provide an overview of the wide range of applications described for various compounds from and preparations of these plants and survey the recent patents related to those applications.
越橘属是一类灌木,其中包括蔓越莓、越橘和蓝莓等多种植物,它们能结出可食用的果实。长期以来,人们都知道食用这些植物的果实以及用其压榨出的果汁对健康有益。从这些植物的果实和种子中提取出了多种功能性化合物。据报道,花青素和相关化合物具有抗菌、抗氧化和抗炎特性。这些果实的提取物已被用于抗衰老制剂中抑制非酶糖基化。蔓越莓籽的油富含抗氧化剂,是ω-3、ω-6和ω-9脂肪酸的来源,使其成为一种有吸引力的化妆品成分。已报道这些果实的提取物具有抑制肿瘤生长、血管生成和转移的作用。这些植物的提取物还被用于开发抗菌涂料。在此,我们概述了这些植物的各种化合物及其制剂的广泛应用,并调查了与这些应用相关的近期专利。