脊髓性肌阵挛：丙戊酸钠与L-5-羟色氨酸联合治疗成功案例
Spinal myoclonus: successful treatment with the combination of sodium valproate and L-5-hydroxytryptophan.
作者信息
Jiménez-Jiménez F J, Roldan A, Zancada F, Molina-Arjona J A, Fernandez-Ballesteros A, Santos J
机构信息
Unidad de Neurología, Hospital Na Sra, Virgen del Puerto, Plasencia, Cáceres, Spain.
出版信息
Clin Neuropharmacol. 1991 Apr;14(2):186-90.
PMID:2015615
Abstract
We describe a 37-year-old man with spinal segmental myoclonus characterized by symmetric, rhythmic contractions of the abdomen with a frequency ranging between 100 and 150/min. The combination of sodium valproate and L-5-hydroxytryptophan was useful to control the myoclonus. We comment on the possible role of the serotonergic system in this syndrome.
摘要
我们描述了一名37岁患有脊髓节段性肌阵挛的男性患者，其特征为腹部对称、有节律的收缩，频率在每分钟100至150次之间。丙戊酸钠和L-5-羟色氨酸联合使用有助于控制肌阵挛。我们对血清素能系统在该综合征中可能发挥的作用进行了评论。
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