Department of Urology, Lukas Hospital, Neuss, Germany.
Urology. 2010 Aug;76(2):480-5. doi: 10.1016/j.urology.2009.10.076. Epub 2010 Feb 13.
To describe our experiences with nephrocutaneous bypass and to assess the role of this procedure as a mean of urinary diversion in patients with incurable ureteral obstruction who are not appropriate candidates for subcutaneous pyelovesical bypass.
Nephrocutaneous bypass was performed on 15 (12 male, 3 female) patients with incurable ureteral obstruction of malignant (n = 13; 87%) or benign (n = 2; 13%) etiology. Only patients with a significant disturbance of the bladder/sphincter-system were eligible for the procedure.
In total, 29 stents were applied using this technique. No major complications were observed perioperatively. The operating time for bilateral nephrocutaneous bypass was 74 (46-102) minutes and for unilateral bypass (1 patient) 38 minutes. Time of indwelling percutaneous nephrostomy before application of nephrocutaneous bypass was 190 (40-870) days. The patients who survived have a mean follow-up of 27 months, whereas for those patients who died the mean follow-up was 7.8 months. Nephrocutaneous bypass resulted in an improved renal function in all patients. Quality of life improvement was reported by all patients, and the objective criteria of "useful life" were met by 13 patients (87%).
Nephrocutaneous bypass is a safe and feasible method to provide effective pyelovesical drainage of urine in patients who have a short-term life expectancy, who are in poor general conditions, or otherwise would need a permanent nephrostomy drainage. The technique offers patients a higher mobility, increased independence resulting in higher quality of life during their final period of life, and may also be applied in nonmalignant patients after careful consideration of alternative urinary diversions.
描述我们在肾皮旁路手术方面的经验,并评估该手术在那些不适合进行皮下肾盂-膀胱旁路手术的、因恶性(n = 13;87%)或良性(n = 2;13%)病因导致不可治愈的输尿管梗阻的患者中作为一种尿液转流手段的作用。
对 15 名(12 名男性,3 名女性)不可治愈的输尿管梗阻的患者进行了肾皮旁路手术,其病因包括恶性(n = 13;87%)或良性(n = 2;13%)。只有那些存在明显的膀胱/括约肌系统障碍的患者才符合该手术的适应证。
总共使用该技术应用了 29 根支架。围手术期无重大并发症。双侧肾皮旁路手术的手术时间为 74 分钟(46-102 分钟),单侧旁路手术(1 例)的手术时间为 38 分钟。在应用肾皮旁路手术之前,经皮肾造瘘术留置的时间为 190 天(40-870 天)。存活患者的平均随访时间为 27 个月,而死亡患者的平均随访时间为 7.8 个月。肾皮旁路手术使所有患者的肾功能均得到改善。所有患者均报告生活质量得到改善,13 名患者(87%)达到了“有用的生活”这一客观标准。
肾皮旁路手术是一种安全可行的方法,可以为那些预期寿命较短、一般情况较差或需要永久性肾造瘘术引流的患者提供有效的肾盂-膀胱尿液引流。该技术为患者提供了更高的活动能力、更高的独立性,从而提高了他们在生命的最后阶段的生活质量,并且在仔细考虑替代尿液转流方式后,也可以应用于非恶性患者。