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外鼻泪管鼻腔造口术后迟发性鼻出血:发生率及危险因素

Delayed epistaxis in external dacryocystorhinostomy: rate and risk factors.

作者信息

Ben Simon Guy J, Cheung Ning, McNab Alan A

机构信息

Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer, Israel.

出版信息

Arch Otolaryngol Head Neck Surg. 2010 Feb;136(2):183-6. doi: 10.1001/archoto.2009.200.

Abstract

OBJECTIVE

To report the incidence and risk factors associated with delayed epistaxis (2-8 days after the procedure) after external dacryocystorhinostomy (DCR).

DESIGN

We identified and analyzed all cases of patients who underwent external DCR procedures at 2 institutions from January 1999 through December 2005. Cases of delayed epistaxis and their final surgical outcome were compared with those without it.

SETTING

All patients who underwent surgery and were examined at 2 public hospitals in Melbourne, Australia.

PATIENTS

A total of 374 patients who underwent 437 DCRs.

INTERVENTIONS

Medical treatment, hospitalization, and endonasal examination with cautery.

MAIN OUTCOME MEASURES

Rate of delayed epistaxis and current and past use of antiplatelet medications.

RESULTS

Of the 374 patients (mean [SD] age, 62 [18] years; 280 [75%] were women) who underwent 437 external DCRs, 15 (3.4%) had an episode of delayed epistaxis. They were generally older and more likely to have a history of active dacryocystitis compared with those who did not develop delayed epistaxis. Preoperative use of aspirin, nonsteroidal anti-inflammatory drugs, or warfarin sodium was not associated with delayed epistaxis or poorer surgical outcome if these anticoagulants were discontinued preoperatively as instructed. None of the 15 patients with delayed epistaxis had continued ingesting anticoagulants before undergoing DCR. Patients who developed epistaxis (80%) had a significantly lower rate of satisfactory surgical outcome than those who did not (90%) (P = .02).

CONCLUSION

The risk of delayed epistaxis should be similar for patients taking or not taking anticoagulant agents if their use is stopped within a defined period of time before DCR.

摘要

目的

报告外路泪囊鼻腔吻合术(DCR)后迟发性鼻出血(术后2 - 8天)的发生率及相关危险因素。

设计

我们识别并分析了1999年1月至2005年12月期间在两家机构接受外路DCR手术的所有患者病例。将迟发性鼻出血病例及其最终手术结果与未发生迟发性鼻出血的病例进行比较。

地点

在澳大利亚墨尔本的两家公立医院接受手术并接受检查的所有患者。

患者

共有374例患者接受了437次DCR手术。

干预措施

药物治疗、住院治疗以及鼻内烧灼检查。

主要观察指标

迟发性鼻出血的发生率以及当前和过去使用抗血小板药物的情况。

结果

在接受437次外路DCR手术的374例患者中(平均[标准差]年龄,62 [18]岁;280例[75%]为女性),15例(3.4%)发生了迟发性鼻出血。与未发生迟发性鼻出血的患者相比,他们通常年龄较大且更有可能有急性泪囊炎病史。如果术前按指示停用这些抗凝剂,术前使用阿司匹林、非甾体抗炎药或华法林钠与迟发性鼻出血或较差的手术结果无关。15例迟发性鼻出血患者中,无一例在接受DCR手术前继续服用抗凝剂。发生鼻出血的患者(80%)手术结果满意的比例显著低于未发生鼻出血的患者(90%)(P = 0.02)。

结论

如果在DCR手术前的规定时间内停用抗凝剂,服用或未服用抗凝剂的患者发生迟发性鼻出血的风险应该相似。

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