University of Vienna, Department of Marine Biology, Althanstrasse 14, A-1090 Vienna, Austria.
Nat Rev Microbiol. 2010 Mar;8(3):218-30. doi: 10.1038/nrmicro2262.
The perpetuation of symbioses through host generations relies on symbiont transmission. Horizontally transmitted symbionts are taken up from the environment anew by each host generation, and vertically transmitted symbionts are most often transferred through the female germ line. Mixed modes also exist. In this Review we describe the journey of symbionts from the initial contact to their final residence. We provide an overview of the molecular mechanisms that mediate symbiont attraction and accumulation, interpartner recognition and selection, as well as symbiont confrontation with the host immune system. We also discuss how the two main transmission modes shape the evolution of the symbiotic partners.
共生体通过宿主世代的延续依赖于共生体的传播。水平传播的共生体由每一代宿主从环境中重新摄取，而垂直传播的共生体通常通过雌性生殖系传递。也存在混合模式。在这篇综述中，我们描述了共生体从最初接触到最终定居的旅程。我们概述了介导共生体吸引和积累、伙伴间识别和选择以及共生体与宿主免疫系统对抗的分子机制。我们还讨论了这两种主要的传播模式如何塑造共生伙伴的进化。
