Yaghoobi Reza, Maraghi Sharif, Bagherani Nooshin, Rafiei Abdolla
Department of Dermatology, Research Center of Thalassemia and Hemoglobinopathy, Jondi Shapour University of Medical Sciences, Ahwaz, Iran.
Korean J Ophthalmol. 2010 Feb;24(1):40-3. doi: 10.3341/kjo.2010.24.1.40. Epub 2010 Feb 5.
Leishmaniasis is a parasitic disease caused by Leishmania species and is classified into three forms; cutaneous, mucocutaneous, and visceral. The eyelid is a rare site involved by leishmaniasis and only makes up 2.5% of cases with cutaneous leishmaniasis (CL). Although CL can affect both upper and lower lids on either their outer or inner aspects, the lateral canthus is most often affected. The most common aspect of lid leishmaniasis is chalazion-like lesions but ulcerous, phagedenic, cancer-like forms, and unilateral chronic granulomatous blepharitis may be observed. When the lid is involved, the disease is usually self-limiting; healing usually takes up to one year, hence early diagnosis and treatment are important. The diagnosis is based on a high index of suspicion regarding the endemicity of the disease in the region. Response to treatment in lid CL cases is quite satisfactory. In this article, we report nine cases of lid leishmaniasis with satisfactory responses to intralesional meglumine antimoniate.
利什曼病是一种由利什曼原虫引起的寄生虫病，分为三种类型：皮肤型、黏膜皮肤型和内脏型。眼睑是利什曼病累及的罕见部位，仅占皮肤利什曼病（CL）病例的2.5%。虽然CL可累及上睑和下睑的外侧或内侧，但外眦最常受累。眼睑利什曼病最常见的表现是睑板腺囊肿样病变，但也可观察到溃疡性、侵蚀性、癌样形式以及单侧慢性肉芽肿性睑缘炎。当眼睑受累时，该病通常为自限性；愈合通常需要长达一年的时间，因此早期诊断和治疗很重要。诊断基于对该地区疾病流行情况的高度怀疑指数。眼睑CL病例对治疗的反应相当令人满意。在本文中，我们报告了9例对病灶内注射葡甲胺锑酸盐反应良好的眼睑利什曼病病例。
