Furuta Yasushi, Matsumura Michiya, Ohtani Fumio, Suzuki Masanobu, Satoh Hiroki, Morita Shinya, Homma Akihiro, Oridate Nobuhiko, Fukuda Satoshi
Department of Otolaryngology-Head & Neck Surgery, Teine-Keijinkai Hospital, Sapporo.
Nihon Jibiinkoka Gakkai Kaiho. 2010 Jan;113(1):9-14. doi: 10.3950/jibiinkoka.113.9.
There is an increased risk of wound complications in patients undergoing salvage laryngectomy following chemoradiotherapy. To reduce the rate of wound complications after a salvage total laryngectomy, a fresh tissue reinforcement of the pharyngeal suture line (pharyngeal interposition graft) has been reported to be useful. In the present study, wound complications after a salvage total laryngectomy with a pectoralis major muscle flap as a pharyngeal interposition graft were analyzed. Four patients with recurrent laryngeal cancer (three with supraglottic, and one with glottic cancer) after chemoradiotherapy underwent salvage total laryngectomy using a pectoralis major muscle interposition flap. Minor wound complications were observed in three of the four patients, with an infection around the tracheostoma, a minor subcutaneous abscess, and a superficial skin necrosis in one patient each. These complications were managed with local wound care. No patients had major wound complications such as pharyngocutaneous fistulas. There were no necroses or wound complications of the pectoralis major muscle flap. This study has suggested that the pectoralis major muscle flap as a pharyngeal interposition graft is safe and useful for prevention of wound complications in salvage total laryngectomy following chemoradiotherapy.
接受放化疗后行挽救性喉切除术的患者出现伤口并发症的风险增加。为降低挽救性全喉切除术后伤口并发症的发生率,据报道,采用新鲜组织加强咽缝合线(咽内置移植片)是有效的。在本研究中,分析了以胸大肌瓣作为咽内置移植片的挽救性全喉切除术后的伤口并发症。4例放化疗后复发性喉癌患者(3例声门上癌,1例声门癌)接受了采用胸大肌内置瓣的挽救性全喉切除术。4例患者中有3例出现轻微伤口并发症,分别为1例气管造口周围感染、1例轻微皮下脓肿和1例浅表皮肤坏死。这些并发症通过局部伤口护理进行处理。没有患者出现诸如咽皮肤瘘等严重伤口并发症。胸大肌瓣没有坏死或伤口并发症。本研究表明,胸大肌瓣作为咽内置移植片对于预防放化疗后挽救性全喉切除术中的伤口并发症是安全且有效的。