Department of Urology, Kaohsiung Medical University Hospital, Taiwan.
Aging Male. 2010 Sep;13(3):179-83. doi: 10.3109/13685531003586975.
This study assessed the possible associations between lower urinary tract symptoms (LUTS) and erectile dysfunction (ED) in aging Taiwanese males and investigated the impact of various aspects of LUTS on ED.
A free health screening for aging males (> or =40 years old) was conducted in Kaohsiung Medical University Hospital. All the subjects had completed clinical data and answered questionnaires. ED and LUTS were assessed by validated symptom scales: the International Index of Erectile Function-5 (IIEF-5) and the International Prostate Symptom Score (IPSS).
A total of 339 eligible patients enrolled in this study with a mean age of 60.1 years old. In multiple logistic regression analysis, age and IPSS (p < 0.001 and p = 0.013, respectively) were significantly associated with ED after controlling other comorbidities. In a further age-adjusted multiple regression analysis, our results showed that irritative symptoms (p = 0.042) have a more significant association with ED than the obstructive symptoms (p = 0.101).
Our results indicate that age and LUTS are the two most independent risk factors for ED. Aging Taiwanese males with LUTS are at increasing risk for ED, especially for those with significant irritative symptoms.
本研究旨在评估下尿路症状(LUTS)与勃起功能障碍(ED)之间在老化台湾男性中的可能关联,并探讨 LUTS 的各个方面对 ED 的影响。
高雄医学大学医院对>40 岁的老年男性进行了免费健康筛查。所有受试者均完成了临床数据和问卷调查。ED 和 LUTS 通过经过验证的症状量表进行评估:国际勃起功能指数-5(IIEF-5)和国际前列腺症状评分(IPSS)。
本研究共纳入 339 名符合条件的患者,平均年龄为 60.1 岁。在多因素逻辑回归分析中,在控制其他合并症后,年龄和 IPSS(分别为 p<0.001 和 p=0.013)与 ED 显著相关。在进一步的年龄调整多元回归分析中,我们的结果表明,刺激症状(p=0.042)与 ED 的关联比阻塞症状(p=0.101)更显著。
我们的结果表明,年龄和 LUTS 是 ED 的两个最独立的危险因素。患有 LUTS 的台湾老年男性发生 ED 的风险增加,尤其是那些具有明显刺激症状的患者。