Health Psychology Section, Department of Psychology, Institute of Psychiatry, King's College London, Bermondsey Wing, 5th Floor, London SE1 9RT, UK.
Implement Sci. 2010 Feb 16;5:17. doi: 10.1186/1748-5908-5-17.
Many interventions shown to be effective through clinical trials are not readily implemented in clinical practice. Unfortunately, little is known regarding how clinicians construct their perceptions of the effectiveness of medical interventions. This study aims to explore general practitioners' perceptions of the nature of 'effectiveness'.
The design was qualitative in nature using the repertory grid technique to elicit the constructs underlying the perceived effectiveness of a range of medical interventions. Eight medical interventions were used as stimuli (diclophenac to reduce acute pain, cognitive behaviour therapy to treat depression, weight loss surgery to achieve weight loss, diet and exercise to prevent type 2 diabetes, statins to prevent heart disease, stopping smoking to prevent heart disease, nicotine replacement therapy to stop smoking, and stop smoking groups to stop smoking). The setting involved face-to-face interviews followed by questionnaires in London Primary Care Trusts. Participants included a random sample of 13 general practitioners.
Analysis of the ratings showed that the constructs clustered around two dimensions: low patient effort versus high patient effort (dimension one), and small impact versus large impact (dimension two). Dimension one represented constructs such as 'success requires little motivation', 'not a lifestyle intervention', and 'health-care professional led intervention'. Dimension two represented constructs such as 'weak and/or minimal evidence of effectiveness', 'small treatment effect for users', 'a small proportion of users will benefit' and 'not cost-effective'. Constructs within each dimension were closely related.
General practitioners judged the effectiveness of medical interventions by considering two broad dimensions: the extent to which interventions involve patient effort, and the size of their impact. The latter is informed by trial evidence, but the patient effort required to achieve effectiveness seems to be based on clinical judgement. Some of the failure of evidence-based medicine to be implemented may be more explicable if both dimensions were attended to.
许多在临床试验中证明有效的干预措施在临床实践中不易实施。遗憾的是,人们对临床医生如何构建他们对医疗干预措施有效性的看法知之甚少。本研究旨在探讨全科医生对“有效性”本质的看法。
该设计本质上是定性的,使用语义差别量表技术来引出一系列医疗干预措施的感知有效性背后的结构。使用了 8 种医学干预措施作为刺激物(双氯芬酸减轻急性疼痛、认知行为疗法治疗抑郁症、减肥手术减肥、饮食和运动预防 2 型糖尿病、他汀类药物预防心脏病、戒烟预防心脏病、尼古丁替代疗法戒烟、以及戒烟小组戒烟)。研究地点是伦敦初级保健信托基金,采用面对面访谈,然后是问卷调查。参与者包括随机抽取的 13 名全科医生。
对评分的分析表明,结构围绕两个维度聚类:低患者努力与高患者努力(维度一),小影响与大影响(维度二)。维度一代表的结构有“成功需要很少的动力”、“不是生活方式干预”和“由医疗保健专业人员主导的干预”。维度二代表的结构有“证据效力弱/几乎没有”、“对使用者的治疗效果小”、“受益的使用者比例小”和“不具有成本效益”。每个维度内的结构密切相关。
全科医生通过考虑两个广泛的维度来判断医疗干预措施的有效性:干预措施涉及患者努力的程度,以及它们的影响大小。后者受试验证据的影响,但实现有效性所需的患者努力似乎基于临床判断。如果关注这两个维度,那么对证据为基础的医学实施失败的一些解释可能会更加清晰。