Department of Radiation Oncology, Albert Einstein Medical Center, 5501 Old York Road, Philadelphia, PA 19141, USA.
Breast. 2010 Feb;19(1):7-9. doi: 10.1016/j.breast.2009.11.004.
For the woman with a newly diagnosed early stage breast cancer, the routine use of pre-operative breast MRI (magnetic resonance imaging) is not indicated beyond conventional breast imaging (i.e., mammography with correlation ultrasound as indicated). There is no consistent evidence that a pre-operative breast MRI confers a benefit to the patient by improving clinical outcomes or surgical procedures. In a meta-analysis of studies reporting on the use of pre-operative breast MRI for the patient with an established index cancer, multifocal or multicentric disease was found on breast MRI in 16% of the patients, a rate substantially higher than the rate of local recurrence after breast conserving surgery plus definitive radiation treatment. In the largest retrospective study of patients treated with breast conserving surgery plus radiation, no gain was found for adding a breast MRI to conventional breast imaging. No randomized clinical trial has been designed to evaluate long term clinical outcomes associated with adding a pre-operative breast MRI. Adding pre-operative breast MRI can alter clinical management in ways that are potentially harmful to patients, for example, increased ipsilateral mastectomies, increased contralateral prophylactic mastectomies, increased work-ups, and delay to definitive surgery. In summary, the routine use of pre-operative breast MRI is not warranted for the typical patient with a newly diagnosed early stage breast cancer.
对于新诊断为早期乳腺癌的女性,除了常规的乳房成像(即乳腺 X 线摄影,必要时结合超声检查)外,不建议常规进行术前乳房 MRI(磁共振成像)检查。没有一致的证据表明术前乳房 MRI 通过改善临床结果或手术程序为患者带来益处。在一项对报告术前乳房 MRI 用于确诊乳腺癌患者的研究的荟萃分析中,发现 16%的患者在乳房 MRI 上存在多灶性或多中心性疾病,这一比率远高于保乳手术后加确定性放疗后的局部复发率。在对接受保乳手术加放疗的患者进行的最大回顾性研究中,添加常规乳房成像对添加乳房 MRI 没有发现获益。没有设计随机临床试验来评估与添加术前乳房 MRI 相关的长期临床结果。添加术前乳房 MRI 可能会以对患者潜在有害的方式改变临床管理,例如增加同侧乳房切除术、增加对侧预防性乳房切除术、增加检查和延迟确定性手术。总之,对于新诊断为早期乳腺癌的典型患者,不建议常规使用术前乳房 MRI。