University of Nebraska Medical Center, Cardiology,981165 Nebraska Medical Center, Omaha, Nebraska 68198-1165, USA.
JACC Cardiovasc Imaging. 2010 Feb;3(2):176-87. doi: 10.1016/j.jcmg.2009.09.024.
This report reviews the development and clinical application of myocardial perfusion imaging with myocardial contrast echocardiography (MCE). This includes the development of microbubble formulations that permit the detection of left ventricular contrast from venous injection and the imaging techniques that have been invented to detect the transit of these microbubbles through the microcirculation. The methods used to quantify myocardial perfusion during a continuous infusion of microbubbles are described. A review of the clinical studies that have examined the clinical utility of myocardial perfusion imaging with MCE during rest and stress echocardiography is then presented. The limitations of MCE are also discussed.
本报告回顾了心肌声学造影（MCE）心肌灌注成像的发展和临床应用。这包括开发允许从静脉注射检测左心室对比的微泡制剂，以及发明的用于检测这些微泡通过微循环的转移动态的成像技术。描述了在连续输注微泡期间定量心肌灌注的方法。然后，回顾了在静息和应激超声心动图期间检查 MCE 心肌灌注成像的临床研究的临床实用性。还讨论了 MCE 的局限性。
