Department of Diagnostic Radiology, University Hospital Freiburg, Hugstetter Strasse 55, 79104 Freiburg, Germany.
Radiology. 2010 Apr;255(1):207-17. doi: 10.1148/radiol.09090860. Epub 2010 Feb 16.
PURPOSE: To prospectively investigate the feasibility, image quality, and radiation dose for prospective electrocardiographically (ECG) triggered sequential dual-source computed tomographic (CT) angiography of the thoracic aorta in comparison to retrospective ECG-gated helical dual-source CT angiography. MATERIALS AND METHODS: This study was approved by the institutional review board; informed consent was obtained. One hundred thirty-nine patients referred for ECG-assisted dual-source CT angiography of the thoracic aorta were prospectively enrolled. Inclusion criteria were stable sinus rhythm and heart rate of 80 beats per minute or less. Tube voltage was adjusted to body mass index (< 25.0 kg/m(2), 100 kV, n = 58; > or = 25.0 kg/m(2), 120 kV, n = 81). In both cohorts, patients were randomly assigned to prospective or retrospective ECG-assisted data acquisition. In both groups, tube current (250 mAs per rotation) was centered at 70% of the R-R cycle. The presence of motion or stair-step artifacts of the thoracic aorta was independently assessed by two readers. Effective radiation dose was calculated from the dose-length product. RESULTS: Subjective scoring of motion and stair-step artifacts was equivalent for both techniques. Scan length was not significantly different (23.8 cm +/- 2.4 [standard deviation] vs 23.7 cm +/- 2.5 for prospective and retrospective ECG-triggered CT angiography, respectively; P = .54). Scanning time was significantly longer for prospective ECG-triggered CT angiography (18.8 seconds +/- 3.4 vs 16.4 seconds +/- 3.3, P < .001). Mean estimated effective dose was significantly lower for prospective data acquisition (100 kV, 1.9 mSv +/- 0.5 vs 4.1 mSv +/- 0.7, P < .001; 120 kV, 5.3 mSv +/- 1.1 vs 9.5 mSv +/- 3.0, P < .001). CONCLUSION: Prospective ECG-gated sequential dual-source CT angiography of the thoracic aorta is feasible, despite the slightly longer acquisition time. Thus, motion-free imaging of the thoracic aorta is possible at significantly lower radiation exposure than retrospective ECG-gated helical dual-source CT angiography in certain patients with a regular heart rate.
目的:前瞻性地研究与回顾性 ECG 门控螺旋双源 CT 血管造影相比,前瞻性心电图(ECG)触发序贯双源 CT(DSCT)血管造影在检查胸主动脉中的可行性、图像质量和辐射剂量。
材料与方法:本研究获得机构审查委员会的批准,并获得了患者的知情同意。前瞻性纳入 139 例因心电图辅助双源 CT 血管造影检查而就诊的患者。纳入标准为窦性心律、心率 80 次/分或以下。根据体质量指数(<25.0 kg/m2,管电压 100 kV,n=58;≥25.0 kg/m2,管电压 120 kV,n=81)调整管电压。在两组中,患者均随机分为前瞻性或回顾性 ECG 辅助数据采集。在两组中,均以 70%的 R-R 间期为中心设定管电流(每次旋转 250 mAs)。由两位读者独立评估胸主动脉的运动伪影和阶梯状伪影的存在情况。根据剂量长度乘积计算有效辐射剂量。
结果:两种技术的运动伪影和阶梯状伪影的主观评分相当。扫描长度无显著差异(前瞻性 ECG 触发 CT 血管造影为 23.8 cm ± 2.4[标准差],回顾性 ECG 触发 CT 血管造影为 23.7 cm ± 2.5;P=0.54)。前瞻性 ECG 触发 CT 血管造影的扫描时间显著延长(18.8 秒 ± 3.4 比 16.4 秒 ± 3.3,P<0.001)。前瞻性数据采集的平均估计有效剂量显著降低(管电压 100 kV 时为 1.9 mSv ± 0.5,比 4.1 mSv ± 0.7 降低,P<0.001;管电压 120 kV 时为 5.3 mSv ± 1.1,比 9.5 mSv ± 3.0 降低,P<0.001)。
结论:尽管采集时间略长,但前瞻性 ECG 门控序贯双源 CT 血管造影检查胸主动脉是可行的。因此,在某些心率规则的患者中,与回顾性 ECG 门控螺旋双源 CT 血管造影相比,可实现更低辐射剂量下的无运动伪影的胸主动脉成像。
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