Ovation Pharmaceuticals, USA.
J Neuropsychiatry Clin Neurosci. 2010 Winter;22(1):105-10. doi: 10.1176/jnp.2010.22.1.105.
Using 10 years' enrollment history, patients with non-drug-induced Parkinson's disease were identified, and the prevalence of Parkinson's disease-induced psychosis (PDP) was estimated using three different claims algorithms based on an expert working group criteria. The estimated prevalence of PDP ranged from 4 to 45/1,000 Parkinson's disease patients. PDP patients were just as likely to be male as female and were significantly older than Parkinson's disease patients without PDP. PDP patients more commonly had evidence of dementia and use of atypical antipsychotics. PDP occurs in up to 45,000 Parkinson's disease patients in the United States but represents a unique neuropsychiatric finding with important treatment implications.
利用 10 年的登记病史，确定了非药物引起的帕金森病患者，并使用基于专家工作组标准的三种不同的理赔算法来估计帕金森病引起的精神病（PDP）的患病率。PDP 的估计患病率为每 1000 例帕金森病患者中有 4 至 45 例。PDP 患者与帕金森病患者无 PDP 的患者一样，男性和女性的比例相当，且明显年龄更大。PDP 患者更常见痴呆和使用非典型抗精神病药物的证据。PDP 在美国多达 45000 例帕金森病患者中发生，但这是一种独特的神经精神发现，具有重要的治疗意义。
