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Differences underlying EGFR and HER2 oncogene addiction.

作者信息

Faber Anthony C, Wong Kwok-Kin, Engelman Jeffrey A

出版信息

Cell Cycle. 2010 Mar 1;9(5):851-2. doi: 10.4161/cc.9.5.11096. Epub 2010 Mar 30.

DOI:10.4161/cc.9.5.11096
PMID:20160489
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2980856/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/134d/2980856/0c43845bde5f/nihms-184806-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/134d/2980856/0c43845bde5f/nihms-184806-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/134d/2980856/0c43845bde5f/nihms-184806-f0001.jpg

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本文引用的文献

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Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19503-8. doi: 10.1073/pnas.0905056106. Epub 2009 Oct 22.
2
Targeting PI3K signalling in cancer: opportunities, challenges and limitations.靶向癌症中的PI3K信号通路：机遇、挑战与局限
Nat Rev Cancer. 2009 Aug;9(8):550-62. doi: 10.1038/nrc2664.
3
NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations.
表皮生长因子受体（ErbB）家族信号传导：癌基因成瘾与个性化肿瘤学的范例
Cancers (Basel). 2017 Apr 12;9(4):33. doi: 10.3390/cancers9040033.
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Inhibition of IGF1R signaling abrogates resistance to afatinib (BIBW2992) in EGFR T790M mutant lung cancer cells.抑制IGF1R信号传导可消除EGFR T790M突变肺癌细胞对阿法替尼（BIBW2992）的耐药性。
Mol Carcinog. 2016 May;55(5):991-1001. doi: 10.1002/mc.22342. Epub 2015 Jun 4.
5
The BCL2 Family: Key Mediators of the Apoptotic Response to Targeted Anticancer Therapeutics.BCL2家族：靶向抗癌治疗凋亡反应的关键调节因子
Cancer Discov. 2015 May;5(5):475-87. doi: 10.1158/2159-8290.CD-15-0011. Epub 2015 Apr 20.
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