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慢性疼痛患者阿片类药物滥用筛查器(SOAPP-R)的效标验证。

Cross-Validation of a Screener to Predict Opioid Misuse in Chronic Pain Patients (SOAPP-R).

机构信息

Inflexxion, Inc., Newton, MA 02464, USA.

出版信息

J Addict Med. 2009 Jun;3(2):66-73. doi: 10.1097/ADM.0b013e31818e41da.

Abstract

OBJECTIVES

The Screener and Opioid Assessment for Patients with Pain - Revised (SOAPP-R) is a self-report questionnaire designed to predict aberrant medication-related behaviors among persons with chronic pain. This measure was developed to complement current risk assessment practices and to improve a clinician's ability to assess a patient's risk for opioid misuse. The aim of this study was to cross-validate the SOAPP-R with a new sample of chronic, non-cancer pain patients.

METHODS

Three hundred and two participants (N=302) prescribed opioids for pain were recruited from five pain management centers in the U.S. Subjects completed a series of self-report measures and were followed for five months. Patients were rated by their treating physician, had a urine toxicology screen, and were classified on the Aberrant Drug Behavior index.

RESULTS

Seventy-three percent (73.2%) of the subjects (N= 221) were followed and 66 participants repeated the SOAPP-R after one week for test-retest reliability. The reliability and predictive validity, as measured by the area under the curve (AUC), were found to be highly significant (test-retest reliability = .91; coefficient alpha = .86; AUC = .74) and were sufficiently similar to values found with the initial sample. A cut-off score of 18 revealed a sensitivity of .80 and specificity of .52.

CONCLUSIONS

Results of this cross-validation study suggest that the psychometric parameters of the SOAPP-R are not based solely on the unique characteristics of the initial validation sample. The SOAPP-R is found to be a reliable and valid screening tool for risk of aberrant drug-related behavior among chronic pain patients.

摘要

目的

筛选和阿片类药物评估用于疼痛患者修订版(SOAPP-R)是一个自我报告问卷旨在预测异常药物相关行为的人患有慢性疼痛。这种措施是为了补充目前的风险评估实践,并提高临床医生评估患者滥用阿片类药物风险的能力。本研究的目的是用新的慢性非癌痛患者样本对 SOAPP-R 进行交叉验证。

方法

从美国的五个疼痛管理中心招募了 302 名接受阿片类药物治疗疼痛的 302 名参与者。受试者完成了一系列自我报告的测量,并随访了五个月。患者由其主治医生进行评估,进行尿液毒理学筛查,并根据异常药物行为指数进行分类。

结果

73%(73.2%)的受试者(N=221)得到了随访,66 名参与者在一周后重复了 SOAPP-R 以进行测试-重测可靠性。发现可靠性和预测效度,以曲线下面积(AUC)衡量,高度显著(测试-重测可靠性=0.91;系数α=0.86;AUC=0.74),并且与初始样本的值非常相似。18 分的截断分数显示出 80%的敏感性和 52%的特异性。

结论

这项交叉验证研究的结果表明,SOAPP-R 的心理测量参数不仅仅基于初始验证样本的独特特征。SOAPP-R 是一种可靠且有效的筛选工具,用于评估慢性疼痛患者异常药物相关行为的风险。

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