Sandberg M A, Lee H, Matthews G P, Gaudio A R
Berman-Gund Laboratory for the Study of Retinal Degenerations, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston.
Invest Ophthalmol Vis Sci. 1991 Apr;32(5):1508-16.
The effect of flash luminance on the relationship of oscillatory potential (OP) amplitude, as a measurement of inner retinal function, to a-wave slope, as a measurement of photoreceptor function, was evaluated in full-field electroretinograms recorded from normal subjects. The ratio of OP amplitude to a-wave slope was found to be independent of flash luminance over a 3000-fold luminance range. This finding raises the possibility that a reduction in the ratio of OP amplitude to a-wave slope in eyes with media opacities may be used as a sign of inner retinal malfunction. Selected cases are presented to illustrate application of this approach.
在从正常受试者记录的全视野视网膜电图中，评估了闪光亮度对作为视网膜内层功能测量指标的振荡电位（OP）振幅与作为光感受器功能测量指标的a波斜率之间关系的影响。发现在3000倍的亮度范围内，OP振幅与a波斜率的比值与闪光亮度无关。这一发现增加了这样一种可能性，即介质混浊眼中OP振幅与a波斜率比值的降低可能被用作视网膜内层功能障碍的一个标志。本文展示了一些选定的病例来说明这种方法的应用。
