带有延长丙酸侧链的原卟啉-IX衍生物的合成。
Syntheses of protoporphyrin-IX derivatives bearing extended propionate side-chains.
作者信息
Holmes Robert T, Lu Jianming, Mwakwari Celinah, Smith Kevin M
出版信息
ARKIVOC. 2009 May 29;2010(5):5-16. doi: 10.1901/jaba.2009.2010-5.
Abstract
In order to investigate the relationship between depth within membranes of singlet oxygen generation and effectiveness of photodynamic therapy of tumors, analogs of protoporphyrin-IX 1 bearing five 4 and seven 5 carbon atoms (in place of the 3-carbon atom chain in 1) were synthesized from monopyrrole precursors.
摘要
为了研究单线态氧生成在膜内的深度与肿瘤光动力治疗效果之间的关系，由单吡咯前体合成了原卟啉-IX 1的类似物，这些类似物带有五个4碳原子和七个5碳原子（取代1中的3碳原子链）。
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