Dhopesh V, Maany I, Herring C
Inpatient Substance Abuse Treatment and Research Unit, Philadelphia Veterans Administration Medical Center, Pennsyvania 19104.
Headache. 1991 Jan;31(1):17-9. doi: 10.1111/j.1526-4610.1991.hed3101017.x.
In a questionnaire survey of inpatient polysubstance abusers it was found that cocaine relieved migraine-type headaches much more often in chronic headache sufferers than in those with only occasional headaches (p less than .05). However, cocaine could also bring on headaches after several hours, both in chronic headache sufferers and in those not subject to headaches. The facts that cocaine may relieve headache immediately, and also may precipitate headaches several hours after use, suggests that the well-known vasoconstrictive actions of cocaine may be responsible. Migraineurs seem more susceptible to some of these effects of cocaine than are people without chronic headaches.
在一项针对住院多药滥用者的问卷调查中发现，对于慢性头痛患者，可卡因缓解偏头痛型头痛的频率远高于偶尔头痛的患者（p小于0.05）。然而，无论是慢性头痛患者还是无头痛史的人，使用可卡因数小时后都可能引发头痛。可卡因既能立即缓解头痛，又可能在使用数小时后引发头痛，这表明可卡因众所周知的血管收缩作用可能是原因所在。与无慢性头痛的人相比，偏头痛患者似乎对可卡因的某些作用更敏感。
