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贝宁和刚果的柠檬桉(Cymbopogon nardus (L) Rendle)精油的化学性质和镇痛特性比较

Comparative chemical and analgesic properties of essential oils of Cymbopogon nardus (L) Rendle of Benin and Congo.

作者信息

Abena A A, Gbenou J D, Yayi E, Moudachirou M, Ongoka R P, Ouamba J M, Silou T

机构信息

Laboratoire de Biochimie et Pharmacologie, Faculté des Sciences de la Santé, Université Marien NGouabi, BP: 69, Brazzaville, Congo.

出版信息

Afr J Tradit Complement Altern Med. 2007 Feb 16;4(3):267-72. doi: 10.4314/ajtcam.v4i3.31218.

Abstract

The chemical and analgesic comparison of essential oils of Cymbopogon nardus (L) Rendle of Benin and Congo was investigated. The chemical analysis wa carried out by using GS/MS for identification of components of the two essential oils while acetic acid-induced writhings, hot plate and tail flick test models were used for analgesic activity. The results showed that the two essential oils exhibited comparable activity on acetic acid-induced writhings, however, the essential oil of Benin induced more significant effect on hot plate model while the Congolese specie showed more effect in the tail flick test. These observations could be explained by some qualitative and/or quantitative differences observed between the constituents of the two essential oils studied.

摘要

对来自贝宁和刚果的柠檬桉(Cymbopogon nardus (L) Rendle)精油进行了化学和镇痛比较研究。通过气相色谱/质谱联用(GS/MS)对两种精油的成分进行化学分析鉴定,同时采用醋酸诱导扭体、热板法和甩尾试验模型检测镇痛活性。结果表明,两种精油在醋酸诱导扭体试验中表现出相当的活性,然而,贝宁的精油在热板模型上诱导的效果更显著,而刚果的品种在甩尾试验中表现出更强的效果。这些观察结果可以用所研究的两种精油成分之间观察到的一些定性和/或定量差异来解释。

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