Muazu J, Kaita A H
Deparment of Pharmaceutical Services, University of Maiduguri Teaching Hospital, Nigeria.
Afr J Tradit Complement Altern Med. 2008 Jun 18;5(4):387-90. doi: 10.4314/ajtcam.v5i4.31294.
Five prescriptions used in the treatment of epilepsy amongst the Hausa/Fulani tribe of Northern Nigeria were collected from traditional healers. The five prescriptions containing eight plants were reviewed as in literature to ascertain scientific basis of their use in treatment of epilepsy. Securidaca longipedunculata (family Polygalaceace) was reported to have such property; Mitragyna inermis (family Rubiaceae) has alkaloids structurally similar to clinically useful anticonvulsant. Celtis integrefolia (family Ulmaceae) was reported to contain gamma amino butyric acid (GABA) that its deficiency may lead to convulsions. The remaining plants were basically helpful in alleviation of associated symptoms of epilepsy except Centaurea praecox (family Asteraceae) which was reported to have neurotoxic substances that may worsen the disease.
从尼日利亚北部豪萨/富拉尼部落的传统治疗师那里收集了五种用于治疗癫痫的药方。对这五种包含八种植物的药方进行了文献综述，以确定它们用于治疗癫痫的科学依据。据报道，长柄刺核藤（远志科）具有这样的特性；无柄帽柱木（茜草科）含有结构上与临床有用的抗惊厥药相似的生物碱。据报道，全缘朴（榆科）含有γ-氨基丁酸（GABA），其缺乏可能导致惊厥。其余植物基本上有助于缓解癫痫的相关症状，除了早熟矢车菊（菊科），据报道它含有可能使病情恶化的神经毒性物质。
