Departamento de Quimica Organica, Facultad de Quimica, Universidad de Murcia, Campus de Espinardo, Murcia-30.100, Spain.
Chem Commun (Camb). 2010 Mar 7;46(9):1394-403. doi: 10.1039/b922531e. Epub 2010 Jan 27.
Despite their high degree of flexibility, tribenzylamine molecules endowed with one ureido group in every arm are avid self-assemblers with a high capacity for self-recognition. Narcissistic self-sorting or chiral self-discrimination events take place when two modules associate giving capsular aggregates. The size of the cavity may be modulated by the relative position of the ureido group and the amino function works as a pH switch of the rupture-reassembly process. When chiral racemic triureas are present the self-assembly is highly diastereoselective.
尽管三苄基胺分子具有很高的灵活性，但每个臂上都有一个脲基的分子却是具有高自我识别能力的自组装体。当两个模块结合形成胶囊状聚集体时，就会发生自恋性自分类或手性自歧视事件。腔的大小可以通过脲基和氨基官能团的相对位置进行调节，而氨基官能团则作为破裂-重组过程的 pH 开关。当存在手性外消旋三脲时，自组装具有高度的非对映选择性。
