碳纳米管-DNA 杂交荧光传感器用于灵敏和选择性检测汞（II）离子。
Carbon nanotube-DNA hybrid fluorescent sensor for sensitive and selective detection of mercury(II) ion.
机构信息
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, Jilin, P. R. China.
出版信息
Chem Commun (Camb). 2010 Mar 7;46(9):1476-8. doi: 10.1039/b921191h. Epub 2010 Jan 20.
DOI:10.1039/b921191h
PMID:20162153
Abstract
Mercury ion (Hg(2+)) is able to specifically bind to the thymine-thymine (T-T) base pair in a DNA duplex and single-walled carbon nanotubes (SWNTs) can effectively quench fluorescence of the dye tethered to the DNA, which enables fluorescent detection of Hg(2+) in aqueous solution with high selectivity and sensitivity.
摘要
汞离子（Hg(2+)）能够特异性地与 DNA 双链体中的胸腺嘧啶-胸腺嘧啶（T-T）碱基对结合，而单壁碳纳米管（SWNTs）可以有效地猝灭与 DNA 连接的染料的荧光，这使得可以在水溶液中对 Hg(2+)进行高选择性和高灵敏度的荧光检测。
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