School of Material Science & Engineering, Nanyang Technological University, Singapore, 639798, Singapore.
Lab Chip. 2010 Mar 7;10(5):634-8. doi: 10.1039/b918566f. Epub 2009 Dec 17.
Monitoring of environmental pollutants has become increasingly important due to concern over potential health and environmental impact inflicted by these chemicals. In this contribution, we focus on the development of an all-plastic biosensor comprising laminated single-walled carbon nanotubes as the active element and its conductance modulation in a liquid-gated field effect transistor, as the principle of transduction, for the detection of 2,4-dicholorophenoxy acetic acid (2,4-D) herbicide. The reported biosensor is capable of performing real-time label-free detection of analytes in liquid environment. This biosensor which relies on immunoassay principle for specificity is able to detect down to 500 fM levels of 2,4-D in soil samples.
由于担心这些化学物质对健康和环境可能造成的影响，环境污染物的监测变得越来越重要。在本研究中，我们专注于开发一种全塑料生物传感器，其包含层压的单壁碳纳米管作为活性元件，并在液体门控场效应晶体管中实现其电导调制，作为传导的原理，用于检测 2,4-二氯苯氧乙酸（2,4-D）除草剂。所报道的生物传感器能够在液体环境中实时进行无标记物检测。这种基于免疫测定原理的生物传感器具有特异性，能够检测到土壤样品中低至 500 fM 水平的 2,4-D。
