Kubota Suguru, Wakasa Satoru, Ooka Tomonori, Tachibana Tsuyoshi, Shiiya Norihiko, Matsui Yoshiro
Department of Cardiovascular Surgery, Hokkaido University Hospital, Kita-ku, Sapporo, Japan.
J Artif Organs. 2010 Apr;13(1):48-50. doi: 10.1007/s10047-010-0483-2. Epub 2010 Feb 17.
A case of Carpentier-Edwards PERIMOUNT (CEP) mitral pericardial bioprosthesis explanted 22 years after the valve replacement is reported. This patient underwent the previous replacement at the age of 50. The extracted bioprosthesis showed three rigid leaflets, one of which had a tear causing severe mitral regurgitation. The X-ray demonstrated calcification of varied extent among these leaflets, ranging from none to severe. When leaflet calcification is suppressed, perhaps the lifespan of a CEP valve can be prolonged more than previously expected. When a literature search was conducted, this case was found to represent the longest reported interval from the implantation of a CEP valve in the mitral position to the explantation as a result of severe mitral regurgitation caused by structural valve deterioration (SVD).
本文报道了一例在瓣膜置换术后22年取出的Carpentier-Edwards PERIMOUNT（CEP）二尖瓣心包生物瓣膜病例。该患者50岁时接受了此前的瓣膜置换手术。取出的生物瓣膜显示有三个僵硬的瓣叶，其中一个有撕裂，导致严重二尖瓣反流。X线显示这些瓣叶钙化程度不一，从无到重度。当瓣叶钙化得到抑制时，或许CEP瓣膜的使用寿命可以比之前预期的延长更多。在进行文献检索时，发现该病例代表了二尖瓣位植入CEP瓣膜至因结构性瓣膜退变（SVD）导致严重二尖瓣反流而取出的报道中最长的间隔时间。
