Japan Scientific Feeds Association, Chuo, Tokyo, Japan.
Anim Sci J. 2010 Feb;81(1):94-101. doi: 10.1111/j.1740-0929.2009.00718.x.
This study examined the influence of transgenic event CBH (StarLink; SL)-derived hybrid corn on growth, health and physiological functions of pigs, as well as the possibility of transferring the cry9C gene or Cry9C protein to the blood, liver or muscles, in comparison with pigs fed a diet with non-transgenic (isogenic) corn (non-SL). The diet for the SL group was composed of 70% SL corn, and the diet for the non-SL group was composed of 70% non-SL corn. Forty pigs approximately 3 months in age were used in the current experiment. After the pigs were acclimatized to their environment for 7 days, they were fed piglet diets for 7 weeks, and afterwards fed growing-finishing diets until the end of the experiment. There were no significant differences in bodyweight gain, feed intake or feed conversion ratio between the pigs fed SL diet and those of non-SL diet. No abnormalities were observed in the health conditions of either the SL or the non-SL group. Moreover, no significant differences were observed between the two groups in hematological values, histopathological examination and necropsy findings. Although the serum biochemical values within each group were normal, the blood urea nitrogen values of the SL group showed a tendency to be slightly higher than those of the non-SL group. Also, the blood glucose values of the SL group were significantly lower than those of the non-SL group. However, the cause of the significant differences in the blood glucose values between the two groups is unknown. The PCR and ELISA did not detect the cry9C gene and Cry9C protein in the blood, liver or muscles of the pigs at the end of the experiment.
本研究旨在探讨转基因事件 CBH（StarLink；SL）衍生杂交玉米对猪的生长、健康和生理功能的影响，以及与喂食非转基因（同基因）玉米（非 SL）相比，Cry9C 基因或 Cry9C 蛋白转移到血液、肝脏或肌肉中的可能性。SL 组的饮食由 70%的 SL 玉米组成，非 SL 组的饮食由 70%的非 SL 玉米组成。本实验使用了大约 3 个月大的 40 头猪。猪适应环境 7 天后，喂食仔猪饲料 7 周，然后喂食生长-育肥饲料，直至实验结束。喂食 SL 饮食的猪与喂食非 SL 饮食的猪的体重增加、饲料摄入量或饲料转化率没有显著差异。SL 组和非 SL 组的猪健康状况均无异常。此外，两组在血液学值、组织病理学检查和尸检结果方面没有显著差异。虽然每组的血清生化值均正常，但 SL 组的血尿素氮值略高于非 SL 组。此外，SL 组的血糖值明显低于非 SL 组。然而，两组血糖值存在显著差异的原因尚不清楚。PCR 和 ELISA 未在实验结束时检测到猪血液、肝脏或肌肉中的 Cry9C 基因和 Cry9C 蛋白。
