直接观察短程治疗中的痰涂片显微镜检查：需要三份样本吗？一项分析及其对结核病控制的影响
Sputum smear microscopy in DOTS: Are three samples necessary? An analysis and its implications in tuberculosis control.
作者信息
Rao Sukhesh
机构信息
Department of Tuberculosis and Respiratory Diseases, Yenepoya Medical College, Deralakatte, Mangalore - 575 018, Karnataka, India.
出版信息
Lung India. 2009 Jan;26(1):3-4. doi: 10.4103/0970-2113.45196.
OBJECTIVES
To assess relevance of spot morning spot (SMS) method of smear microscopy in tuberculosis control by directly observed treatment short course (DOTS).
MATERIALS AND METHODS
Screening of smear microscopy results of 546 cases of pulmonary tuberculosis at our DOTS centre.
RESULTS
Among 546 cases, 82% had all three samples positive for AFB, 98% had either morning sample or spot and morning sample positive. 2% had second spot sample positive.
CONCLUSION
Examination of third sample, especially second spot sample, does not add significantly to the diagnostic yield. Examination of one spot and early morning samples were able to correctly diagnose 98% cases. This has strong implications in DOTS strategies.
目的
通过直接观察短程治疗（DOTS）评估痰涂片显微镜检查的即时晨痰（SMS）方法在结核病控制中的相关性。
材料与方法
对我们DOTS中心546例肺结核病例的痰涂片显微镜检查结果进行筛查。
结果
在546例病例中，82%的所有三个样本抗酸杆菌均呈阳性，98%的晨痰样本或即时痰及晨痰样本呈阳性。2%的第二个即时痰样本呈阳性。
结论
第三个样本，尤其是第二个即时痰样本的检查对诊断阳性率的提高没有显著增加。一个即时痰和清晨痰样本的检查能够正确诊断98%的病例。这对DOTS策略有重要意义。
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