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经皮血管成形术治疗非中层纤维肌发育不良的技术和临床结果:30 例单侧肾动脉狭窄血管内治疗的结果。

Technical and clinical results after percutaneous angioplasty in nonmedial fibromuscular dysplasia: outcome after endovascular management of unifocal renal artery stenoses in 30 patients.

机构信息

Service d'imagerie médicale, Hôpital de Rangueil, (Rangueil) Bâtiment H1, R.D.C, 1 avenue du Professeur Jean Poulhès, TSA 50032-31059, Toulouse Cedex 9, France.

出版信息

Cardiovasc Intervent Radiol. 2010 Apr;33(2):270-7. doi: 10.1007/s00270-010-9818-x. Epub 2010 Feb 18.

Abstract

Although percutaneous transluminal renal angioplasty (PTRA) is associated with excellent results in medial fibromuscular dysplasia (FMD), the clinical and technical outcome in the less common nonmedial subtype of FMD is not clearly known. Angiographic PTRA results and clinical follow-up were documented, to report technical and clinical results in 30 patients with unifocal, nonmedial dysplastic stenoses. Balloon angioplasty was technically successful in only 65% of the lesions. Additional stenting, performed after PTRA failure in six patients, increased the initial technical success rate to 82%. Stenting was used in another lesion after restenosis, and long-term patency was achieved in only three of the seven stented lesions. Frequent restenoses and unusual complications were observed during follow-up. Stent fracture occurred in two cases. Overall, long-term clinical and technical successes were sustained in 70 and 76%, respectively. We conclude that nonmedial, unifocal renal artery dysplastic stenoses do not share the excellent prognosis of the medial type and that stenting should be avoided. Therefore, surgery should be considered in lesions remaining unresponsive to balloon dilatation, after a second PTRA attempt.

摘要

虽然经皮腔内肾血管成形术(PTRA)在治疗中层纤维肌发育不良(FMD)方面效果显著,但在较少见的非中层亚型 FMD 中的临床和技术效果尚不清楚。本文记录了经皮腔内肾血管成形术的结果和临床随访情况,报告了 30 例局灶性、非中层纤维肌发育不良性狭窄患者的技术和临床结果。仅 65%的病变球囊血管成形术获得技术成功。在 6 例 PTRA 失败后进行支架置入术,将初始技术成功率提高至 82%。另一个病变在再狭窄后进行了支架置入,只有 7 个支架置入病变中有 3 个获得了长期通畅。在随访期间观察到频繁的再狭窄和不寻常的并发症。在两个病例中发生了支架断裂。总的来说,长期临床和技术成功率分别为 70%和 76%。我们的结论是,非中层、局灶性肾动脉纤维肌发育不良性狭窄与中层型的良好预后不同,应避免支架置入。因此,在第二次 PTRA 尝试后,对于对球囊扩张无反应的病变,应考虑手术治疗。

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