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头颈部皮肤肿瘤切除术后全厚皮片及软骨膜皮片移植。

Full-thickness skin grafts and perichondrial cutaneous grafts following surgical removal of cutaneous neoplasms of the head and neck.

机构信息

Department of Otolaryngology, Facial Plastic and Reconstructive Surgery, Lange Land Hospital, Toneellaan 1, 2725 KJ, Zoetermeer, The Netherlands.

出版信息

Eur Arch Otorhinolaryngol. 2010 Aug;267(8):1277-83. doi: 10.1007/s00405-010-1210-6. Epub 2010 Feb 18.

DOI:10.1007/s00405-010-1210-6
PMID:20165953
Abstract

The objective of the study is to determine efficacy in terms of survival rate and cosmesis of "normal" full-thickness skin grafts (FTSGs) as compared to perichondrial cutaneous grafts (PCCGs) in facial reconstruction. A chart review of all facial reconstructions using FTSGs and PCCGs between 1995 and 2005 was undertaken. All patients were treated by the same surgeon. A total of 121 skin grafts were included in this study (70 FTSGs and 51 PCCGs). All patients were examined at days 5 and 10 to assess the viability of the graft. For esthetic evaluation, 70 photographs were available with a minimum follow-up of 6 months (42 FTSGs/59% of total; 28 PCCGs/54% of total). The photos were randomly shown to three raters, who had no previous knowledge about the graft being a FTSG or PGCG. The complete take rate of the FTSGs and of the PCCGs was respectively, 87% (9 failures) and 94% (3 failures) .This is no statistically significant difference (P = 0.1857). The cosmetic outcome of PCCGs overall scored better by the three raters. However, the esthetic rating between PCCG and FTSG was of no statistical significant difference (P = 0.06). In conclusion, both FTSGs and PCCGS are viable options in facial reconstruction, with no statistical difference in survival and cosmesis. They are simple and one-stage procedures. The PCCG is a smooth graft, containing a few sebaceous glands and possibly has less contraction.

摘要

本研究旨在比较正常全厚皮片(FTSG)与软骨膜皮片(PCCG)在面部重建中存活率和美容效果的差异。对 1995 年至 2005 年间使用 FTSG 和 PCCG 进行的所有面部重建的图表进行了回顾性分析。所有患者均由同一位外科医生治疗。本研究共纳入 121 例皮片(70 例 FTSG 和 51 例 PCCG)。所有患者均在第 5 天和第 10 天接受检查,以评估移植物的存活情况。为了进行美学评估,有 70 张照片可供使用,随访时间至少为 6 个月(42 例 FTSG/总病例的 59%;28 例 PCCG/总病例的 54%)。这些照片随机展示给 3 位评估者,他们事先不知道移植物是 FTSG 还是 PCCG。FTSG 和 PCCG 的完全成活率分别为 87%(9 例失败)和 94%(3 例失败),无统计学差异(P=0.1857)。PCCG 的整体美学效果总体上得到了三位评估者的更好评分。然而,PCCG 和 FTSG 的美学评分无统计学差异(P=0.06)。结论:FTSG 和 PCCG 均为面部重建的可行选择,在存活率和美容效果方面无统计学差异。它们是简单的单阶段手术。PCCG 是一种光滑的移植物,含有少量皮脂腺,可能收缩较少。

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本文引用的文献

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2
Secondary intention healing after excision of nonmelanoma skin cancer of the head and neck: statistical evaluation of prognostic values of wound characteristics and final cosmetic results.头颈部非黑色素瘤皮肤癌切除术后二期愈合:伤口特征及最终美容效果预后价值的统计学评估
Plast Reconstr Surg. 2008 Dec;122(6):1747-1755. doi: 10.1097/PRS.0b013e31818a9aaa.
3
Complications after nasal skin repair with local flaps and full-thickness skin grafts and implications of patients' contentment.
局部皮瓣和全厚皮片修复鼻皮肤后的并发症及患者满意度的影响
Oral Maxillofac Surg. 2009 Mar;13(1):15-9. doi: 10.1007/s10006-008-0139-z.
4
The perichondrial cutaneous graft: a facial reconstructive option for the ages (ages 1 week to 94 years).软骨膜皮瓣移植:适用于各年龄段(1周龄至94岁)的面部重建选择。
Laryngoscope. 2008 Oct;118(10):1753-7. doi: 10.1097/MLG.0b013e31817f188b.
5
Minimally invasive options for cutaneous defects: secondary intention healing, partial closure, and skin grafts.皮肤缺损的微创治疗选择:二期愈合、部分缝合和皮肤移植。
Facial Plast Surg Clin North Am. 2005 May;13(2):215-30, v. doi: 10.1016/j.fsc.2004.11.008.
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Clinical appearance of full-thickness skin grafts of the nose.鼻部全厚皮片的临床表现。
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Br J Ophthalmol. 2005 Feb;89(2):219-22. doi: 10.1136/bjo.2004.052639.
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The early circulation in split skin grafts.自体断层皮片的早期血液循环
Acta Chir Scand. 1962 Jul;124:11-8.