糖尿病中的胃功能障碍：新兴技术与药理学
Stomach dysfunction in diabetes mellitus: emerging technology and pharmacology.
作者信息
Szarka Lawrence A, Camilleri Michael
机构信息
Clinical Enteric Neuroscience Translational and Epidemiological Research (CENTER), College of Medicine, Mayo Clinic, Rochester, Minnesota.
出版信息
J Diabetes Sci Technol. 2010 Jan 1;4(1):180-9. doi: 10.1177/193229681000400123.
Abstract
Gastroparesis and other types of gastric dysfunction result in substantial morbidity in diabetes patients. The pathophysiology of these disorders is incompletely understood. This article reviews techniques applicable to the assessment of gastric function in diabetes patients, including the measurement of emptying, accommodation, and contractility. Available treatment options are also reviewed, including novel yet unapproved serotonin 5-HT(4) agonist pharmacological treatments, as well as the role of endoscopic, surgical, and device treatments of gastroparesis.
摘要
胃轻瘫及其他类型的胃功能障碍在糖尿病患者中导致了相当高的发病率。这些病症的病理生理学尚未完全明了。本文综述了适用于评估糖尿病患者胃功能的技术，包括胃排空、胃容纳及胃收缩性的测量。还综述了现有的治疗选择，包括新型但尚未获批的5-羟色胺5-HT(4)激动剂药物治疗，以及胃轻瘫的内镜、手术和器械治疗的作用。
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